CAS · 2958-36-3
Product Overview
2-Amino-2,5-dichlorobenzophenone is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Yellow crystalline solid |
|---|---|
| Purity (HPLC): | 98% min |
| Assay (HClO4 0.1N): | 96% min |
| Identification (HPLC): | Under IR detection, the characteristic peak of the test sample is consistent with that of the standard sample. Under HPLC detection, the retention time of the main peak of the test sample should be consistent with that of the standard sample |
| Water (KF): | 1.0% max |
| Loss on drying: | 1.0% max |
| P-Chloroaniline: | 110 ppm max |
| IPM.A: | 0.5% max |
| IPM.POSTA: | 1.0% max |
| IPM.B: | 0.5% max |
| Largest single impurity: | 0.1% max |
| Total impurity: | 2.0% max |
Applications
2-Amino-2,5-dichlorobenzophenone is a multifunctional aromatic ketone widely used as an intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. Its amino and dichloro-substituted benzophenone structure allows for selective reactions such as nucleophilic substitution, condensation, and coupling, making it suitable for the synthesis of heterocycles, enzyme inhibitors, and other bioactive compounds. It is commonly employed in medicinal chemistry for the development of antiviral, anticancer, and CNS-active molecules. In addition, it serves as a building block in dye and pigment chemistry, enabling the introduction of functional groups for color modification and stabilization.
Benefits
The compound offers high chemical stability and versatility due to its aromatic ketone backbone and reactive substituents. The dichloro groups increase electrophilicity and facilitate selective derivatization, while the amino group provides a site for further functionalization. Its solubility in common organic solvents and compatibility with various reaction conditions allow reproducible multi-step syntheses and high yields. This combination of stability, reactivity, and functional diversity makes it a valuable intermediate in pharmaceutical and chemical research.
Conclusion
2-Amino-2,5-dichlorobenzophenone is a highly useful intermediate in pharmaceuticals, agrochemicals, and fine chemical synthesis. Its multifunctional aromatic structure enables efficient chemical transformations, selective derivatization, and the preparation of bioactive molecules and functionalized intermediates, supporting advanced research and industrial applications.
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