CAS · 25086-89-9
Product Overview
Poly(1-vinylpyrrolidone-co-vinyl acetate) is a high-purity pharmaceutical-excipients supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Item | Specification |
|---|---|
| Grade | USP-NF 2024 and EP11 |
| Appearance | White or yellowish-white, hygroscopic powder or flakes |
| Solubility | Freely soluble in water, ethanol (96%), and methylene chloride |
| Identification A, B, C | Positive |
| Appearance of Solution | Not more opalescent than reference suspension II; color ≤ B5, R5 or BY5 |
| pH (10% solution) | 3.0 – 7.0 |
| Viscosity (K-value) | 27.0 – 33.0 |
| Aldehydes (as Acetaldehyde) | Max 500 ppm |
| Peroxides (as H2O2) | Max 400 ppm |
| Hydrazine | Max 1 ppm |
| 1-Vinylpyrrolidin-2-one | Max 10 ppm |
| Vinyl acetate | Max 10 ppm |
| 2-Pyrrolidone | Max 0.5% |
| Heavy metals | Max 10 ppm |
| Cd* | Max 0.5 ppm |
| Pb* | Max 0.5 ppm |
| As* | Max 1.5 ppm |
| Hg* | Max 3 ppm |
| V* | Max 10 ppm |
| Co* | Max 5 ppm |
| Ni* | Max 20 ppm |
| Loss on Drying | Max 5.0% |
| Water | Max 5.0% |
| Sulfate Ash / Residue on Ignition | Max 0.1% |
| Copolymerized Vinyl Acetate Content | 35.3 – 41.4% |
| Assay (Nitrogen content) | 7.0 – 8.0% |
| Microbiological Status* | Max 100 CFU/g (aerobic plate count) Max 100 CFU/g (mold and yeast) No Escherichia coli /g No Pseudomonas aeruginosa /g No Salmonella /10g No Staphylococcus aureus /g |
Applications
1. Personal Care and Cosmetics
Poly(1-vinylpyrrolidone-co-vinyl acetate)丨CAS 25086-89-9is a key ingredient in hair, skin, and beauty products, known for forming flexible, breathable, and clear films. Its applications include:
a. Hair Styling Products
● Found in hair gels, sprays, mousses, and waxes.
● Provides:
Excellent hold and style retention
Gloss and smooth texture
Resistance to humidity (anti-frizz)
b. Skincare and Color Cosmetics
● Used in foundations, BB creams, and lotions.
● Acts as:
Film former
Stabilizer
Fixative for pigments
c. Sunscreens and SPF Formulas
● Enhances water resistance and UV filter adhesion on the skin.
2. Pharmaceutical Industry
In pharmaceutical formulations, especially oral solid dosage forms, the VP/VA copolymer serves as:
● Tablet binder and film coating agent
● Dispersing agent in dry suspensions
● Stabilizer for poorly soluble APIs (used in solid dispersions)
Benefits in pharmaceuticals:
● Improves tablet integrity
● Enhances drug bioavailability
● Allows controlled release formulations
3. Industrial and Household Products
The polymer's excellent film-forming and adhesive properties also make it suitable in:
a. Adhesives
● Employed in water-based adhesives for paper, labels, and packaging
● Offers tackiness, quick setting, and clean removability
b. Paints and Coatings
● Used in architectural coatings as a film former and binder
● Contributes to washability, adhesion, and surface finish
c. Textile Finishes
● Acts as a coating agent to enhance texture and anti-pilling properties
4. Agricultural Formulations
In agrochemical formulations, the VP/VA copolymer serves as:
● Binder and dispersant for wettable powders and granules
● Enhances solubility, spreadability, and environmental stability of active ingredients
Benefits
1. Excellent Film Formation
● Forms clear, flexible, and non-tacky films on skin, hair, or surfaces
● Enhances barrier properties, appearance, and longevity of cosmetic and pharmaceutical products
2. Water and Humidity Resistance
● Provides moisture resistance in formulations
● In hair care, it reduces frizz and improves style durability
● In tablets and coatings, it enhances shelf stability
3. Compatibility and Stability
● Non-ionic nature allows compatibility with:
Cationic and anionic actives
Wide pH range (pH 3–9)
Alcohols and water-based systems
● Offers chemical stability and non-reactivity
4. Enhances Drug Solubility and Bioavailability
● Used in solid dispersion systems for poorly water-soluble drugs
● Improves dissolution rate and oral absorption
5. Safe and Biocompatible
● Widely recognized as non-toxic, non-irritating, and biocompatible
● Approved for use in cosmetics, pharmaceuticals, and food packaging (depending on grade and regulatory requirements)
Conclusion
Poly(1-vinylpyrrolidone-co-vinyl acetate)丨CAS 25086-89-9 is a highly functional copolymer used across cosmetic, pharmaceutical, industrial, and agricultural sectors. With its film-forming, adhesive, and solubility-enhancing properties, this copolymer improves product performance, stability, and user experience. Its non-ionic, biocompatible, and customizable nature makes it a versatile and trusted ingredient in modern formulation science.
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Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.