CAS · 39856-50-3
Product Overview
5-Bromo-2-nitropyridine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Yellowish to brown powder |
|---|---|
| Purity (HPLC): | 98% min |
| Identification: | NMR confirm |
| Melting Point: | 147-151 °C |
| Water Content: | 1% max |
Applications
5-Bromo-2-nitropyridine (CAS 39856-50-3) is a halogenated heterocyclic compound widely used as an intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. Its structure, containing both bromine and nitro substituents on a pyridine ring, makes it highly reactive in cross-coupling reactions, nucleophilic substitutions, and reduction chemistry. In pharmaceutical research, it serves as a building block for the synthesis of bioactive pyridine derivatives, including enzyme inhibitors, antiviral agents, and other therapeutic molecules. In agrochemical development, it is employed to prepare herbicides, fungicides, and insecticides where pyridine cores and halogen modifications enhance potency and stability. Additionally, it is used in organic synthesis for constructing complex heterocycles and functionalized aromatic compounds in materials science and chemical research.
Benefits
The benefits of 5-bromo-2-nitropyridine are largely derived from its dual halogen and nitro functionalities, which provide multiple reactive sites for chemical transformations. The bromine atom enables selective palladium-catalyzed cross-coupling reactions, while the nitro group can be readily reduced or substituted to generate diverse derivatives. This versatility facilitates efficient synthesis of complex molecules with precise structural control, accelerating drug discovery and agrochemical development. Its stability under standard laboratory conditions and predictable reactivity make it a reliable intermediate for both research and industrial applications, allowing chemists to design molecules with optimized biological activity and chemical performance.
Conclusion
5-Bromo-2-nitropyridine is a valuable halogenated pyridine intermediate with broad applications in pharmaceuticals, agrochemicals, and advanced organic synthesis. Its combination of reactivity, stability, and structural versatility enables efficient construction of bioactive molecules and functional heterocycles. By supporting innovative chemical design and synthesis, it continues to play a key role in research and industrial applications.
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