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Product Line: Pharmaceutical Chemicals

2-Chloroacrylic acid

CAS 598-79-8

Molecular structure of 2-Chloroacrylic acid

CAS · 598-79-8

01

Product Overview

2-Chloroacrylic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance: Off-white or white solid
Purity: 98% min
03

Applications

2-Chloroacrylic acid is a halogenated unsaturated carboxylic acid widely used as a versatile intermediate in pharmaceutical, agrochemical, and fine chemical synthesis. Its α,β-unsaturated carboxylic structure allows for nucleophilic addition, Michael addition, and condensation reactions, making it suitable for the preparation of acrylate derivatives, heterocycles, and bioactive molecules. In medicinal chemistry, it serves as a building block for synthesizing enzyme inhibitors, antiviral agents, and other pharmacologically active compounds. It is also employed in agrochemical research to develop herbicides and fungicides and in chemical research for the synthesis of specialty chemicals, polymers, and functionalized intermediates.

04

Benefits

The benefits of 2-Chloroacrylic acid derive from its high chemical reactivity, halogen functionality, and synthetic versatility. The α,β-unsaturated system allows efficient addition reactions and conjugate modifications, while the chloro group provides a site for further functionalization through substitution or cross-coupling reactions. Its carboxylic acid group facilitates derivatization into esters, amides, and other functional derivatives, enabling multi-step synthesis. The compound's stability and solubility in organic solvents support reproducible reactions and high yields, making it suitable for laboratory research and scalable industrial applications.

05

Conclusion

2-Chloroacrylic acid is a valuable halogenated unsaturated carboxylic acid intermediate with broad applications in pharmaceuticals, agrochemicals, and fine chemical synthesis. Its combination of α,β-unsaturation, chloro substitution, and carboxylic acid functionality enables diverse chemical transformations and efficient synthesis of bioactive molecules and functionalized intermediates. By supporting selective derivatization and reproducible reactions, it continues to play a key role in organic synthesis, medicinal chemistry, and industrial chemical development.

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