CAS · 2374-03-0
Product Overview
4-Amino-3-hydroxybenzoic acid is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Off white to brown powder |
|---|---|
| Purity (HPLC) | 99% min |
| Water | 1% max |
| Ignition Residue | 1% max |
| m-Hydroxybenzoic Acid | 0.3% max |
| 3-Hydroxy-4-nitrobenzoic Acid | 0.15% max |
| Other Maximum Single Impurity | 0.5% max |
| Total Impurity | 1% max |
Applications
4-Amino-3-hydroxybenzoic acid (CAS 2374-03-0) is an important aromatic amino acid derivative used as an intermediate in pharmaceutical, dye, and agrochemical synthesis. In pharmaceuticals, it serves as a key building block in the production of anti-inflammatory drugs, antibacterial agents, and enzyme inhibitors due to its reactive amino and hydroxyl functional groups. The compound is also employed in the manufacture of azo dyes, where it acts as a coupling component to produce vibrant, stable colors. In polymer and material chemistry, it can be incorporated into functional resins and biocompatible polymers, improving adhesive and optical properties. Additionally, it is used in analytical chemistry and biochemical research for structure–activity studies of substituted benzoic acids.
Benefits
The molecular structure of 4-amino-3-hydroxybenzoic acid provides dual reactivity through its hydroxyl and amino substituents, allowing for selective derivatization and versatile synthetic transformations. It exhibits good solubility in polar solvents and chemical stability under mild conditions, making it a suitable precursor for large-scale industrial applications. Its biocompatible and low-toxicity profile enhances its appeal for use in medical and biological contexts. Moreover, its ability to participate in hydrogen bonding and metal chelation contributes to its use in advanced material science applications, such as coordination polymers and sensing materials.
Conclusion
4-Amino-3-hydroxybenzoic acid is a multifunctional intermediate combining synthetic versatility, safety, and chemical stability. Its broad application across pharmaceuticals, dyes, and advanced materials underscores its importance in both research and industry. With its dual functional groups and strong reactivity, it continues to play a vital role in the development of innovative molecules and high-performance materials.
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