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Product Line: Pharmaceutical Chemicals

2-Cyclohepten-1-one

CAS 1121-66-0

Molecular structure of 2-Cyclohepten-1-one

CAS · 1121-66-0

01

Product Overview

2-Cyclohepten-1-one is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance Colorless to light yellow liquid
Purity (GC) 85.0% min
Identification Consistent with the standard spectrum
Water 0.5% max
03

Applications

1. Organic Synthesis Intermediate

2-Cyclohepten-1-one is widely used as a building block in synthetic organic chemistry. Its cyclic enone structure allows for:

Michael additions

Diels-Alder reactions

Grignard and nucleophilic additions

Synthesis of bridged bicyclic compounds

These transformations are vital in developing complex cyclic frameworks, especially in pharmaceutical and natural product synthesis.

2. Pharmaceutical Research

Due to its reactive α,β-unsaturated ketone group, it is employed in:

Synthesis of drug precursors

Construction of bioactive molecules, such as anti-inflammatory agents and neurologically active compounds

3. Fragrance and Flavor Industry

Although not typically used directly as a fragrance component, it may serve as an intermediate in the manufacture of aroma chemicals, particularly those involving musk or woody notes, due to its cyclic structure and ketone function.

4. Materials Science and Polymer Chemistry

2-Cyclohepten-1-one can be utilized in functional monomer synthesis or as a reactive additive in designing specialty polymers or modifying polymer surfaces.

04

Benefits

✅ Highly Reactive Functional Groups

The α,β-unsaturated ketone moiety offers versatile sites for chemical modification, making it ideal for diverse transformations.

✅ Efficient Ring System

The seven-membered ring allows the synthesis of non-aromatic cyclic intermediates that are crucial in creating structurally unique compounds.

✅ Cost-Effective Intermediate

Its ready availability and low molecular weight make it a cost-efficient starting material in multi-step syntheses.

✅ Useful Scaffold in Medicinal Chemistry

As a cyclic ketone, it is frequently integrated into lead compounds or pharmacophores during drug discovery.

05

Conclusion

2-Cyclohepten-1-one (CAS 1121-66-0) is a valuable and reactive intermediate broadly used in organic synthesis, pharmaceutical development, and materials science. Its combination of a seven-membered ring with an α,β-unsaturated ketone makes it especially useful for constructing complex molecules and biologically active compounds. With multiple functionalization possibilities and wide-ranging applications, it remains an important component in the toolkit of synthetic and medicinal chemists.

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