CAS · 141-30-0
Product Overview
3,6-dichloropyridazine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White crystallized particles |
|---|---|
| Melting Point: | 67–70 °C |
| Content: | 98.0% min |
Applications
1. Pharmaceutical Intermediate
3,6-Dichloropyridazine is widely used in the synthesis of pharmaceutical compounds. The two reactive chlorines enable substitution reactions with various nucleophiles (e.g., amines, thiols, alcohols), leading to diverse bioactive heterocycles. It is a known intermediate in the preparation of anti-inflammatory, anti-cancer, and antimicrobial agents.
2. Agrochemical Synthesis
It is also utilized as a core building block in the synthesis of agrochemicals such as herbicides, fungicides, and insecticides. The pyridazine ring system is often present in compounds with strong biological activity against pests and pathogens.
3. Chemical Intermediate for Heterocycles
The compound is highly valuable in forming functionalized pyridazines and fused ring systems. It undergoes nucleophilic aromatic substitution (SNAr) reactions readily, making it useful for creating complex molecules in both academic and industrial research.
4. Material Chemistry and Dye Industry
3,6-Dichloropyridazine may also serve as an intermediate for the synthesis of pigments, dyes, and fluorescent compounds due to its conjugated heteroaromatic structure.
Benefits
High Reactivity: The chlorines at positions 3 and 6 are highly reactive towards nucleophiles, enabling versatile derivatization.
Synthetic Flexibility: Allows for easy functionalization, providing access to a wide variety of pyridazine derivatives with biological or industrial relevance.
Pharmacophoric Potential: Pyridazine rings are known for their bioactivity; this compound provides a straightforward route to pharmacologically relevant structures.
Symmetrical Structure: Simplifies prediction and control of reaction outcomes in synthesis.
Conclusion
3,6-Dichloropyridazine is a versatile and reactive heterocyclic compound widely employed in the pharmaceutical, agrochemical, and fine chemical industries. Its unique structure and functional reactivity make it a valuable intermediate for developing a broad range of biologically active molecules and advanced materials. As interest in heterocyclic chemistry continues to grow, 3,6-dichloropyridazine remains a key starting material for innovation in drug discovery and chemical synthesis.
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