CAS · 1968-05-4
Product Overview
3,3-Diindolylmethane is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Off-white to white crystalline powder |
|---|---|
| Assay (HPLC) | 99% min |
| Identification | IR |
| Melting Range | 165.0°C ~ 169.0°C |
| Loss on Drying | 0.5% max |
| Residue on ignition | 0.1% max |
| Heavy metal | 10 ppm max |
| Particle size | 98% through 80 mesh |
| Total Plate Count | 1000 cfu/g max |
| Yeasts and molds | 100 cfu/g max |
| Melamine | Negative |
| Salmonella | Negative |
| E. Coli | Negative |
| Pseudomonas | Negative |
| Staphylococcus | Negative |
| Total Coliforms | 10 cfu/g max |
Applications
3,3-Diindolylmethane (DIM) is a bioactive compound derived from the digestion of indole-3-carbinol, which is naturally found in cruciferous vegetables such as broccoli, cauliflower, and Brussels sprouts. DIM is widely used in dietary supplements and nutraceuticals for promoting hormonal balance, particularly in supporting estrogen metabolism. It is applied in formulations targeting men and women to maintain healthy hormone levels, reduce estrogen dominance, and support reproductive health. Additionally, DIM is investigated in research for its potential anti-cancer properties, especially in hormone-sensitive cancers such as breast, prostate, and cervical cancer. Beyond human health, it is also explored in veterinary supplements for hormonal support. DIM is formulated in capsules, tablets, and functional foods, and its stability allows incorporation into a variety of delivery forms.
Benefits
The benefits of 3,3-diindolylmethane arise from its role in modulating estrogen metabolism and supporting overall hormonal balance. It promotes the conversion of stronger, potentially harmful estrogen metabolites into safer forms, reducing risks associated with estrogen dominance. DIM exhibits antioxidant and anti-inflammatory properties, contributing to cellular health and protection against oxidative stress. Research also indicates potential chemopreventive effects, as DIM may influence pathways involved in cancer cell growth and apoptosis. Its natural derivation and compatibility with dietary supplements make it safe and effective for long-term use in adults seeking hormonal support. Additionally, DIM's versatility allows its inclusion in combined formulations with other vitamins, minerals, and plant extracts for comprehensive wellness benefits.
Conclusion
In summary, 3,3-diindolylmethane is a bioactive compound with applications in dietary supplements, hormonal health, and cancer research. Its benefits-including estrogen metabolism support, antioxidant activity, and potential chemopreventive effects-make it a valuable component in promoting hormonal balance and overall wellness. By enabling safe and effective supplementation, 3,3-diindolylmethane continues to play a significant role in nutraceuticals, functional foods, and research on hormone-related health conditions.
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