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Product Line: Pharmaceutical Chemicals

Diethyl 2-(2-cyanoethyl)malonate

CAS 17216-62-5

Molecular structure of Diethyl 2-(2-cyanoethyl)malonate

CAS · 17216-62-5

01

Product Overview

Diethyl 2-(2-cyanoethyl)malonate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance Slight yellow liquid
Purity (GC) 98% min
03

Applications

Diethyl 2-(2-cyanoethyl)malonate is primarily used as a versatile intermediate in organic synthesis, pharmaceutical research, and fine chemical production. It serves as a key building block for the preparation of heterocyclic compounds, substituted malonates, and various bioactive molecules. The compound is commonly applied in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals where the malonate and cyano functionalities enable nucleophilic substitution, condensation, and cyclization reactions. In research laboratories, it is employed to study reaction mechanisms, optimize synthetic pathways, and develop new derivatives with potential biological activity. Its reactive sites make it particularly valuable for constructing carbon–carbon bonds and introducing functional groups in complex molecule synthesis.

04

Benefits

The compound offers several advantages due to its dual functional groups and well-defined structure. The malonate ester provides acidity and enolate formation capability, while the cyano group allows further functionalization through nucleophilic or cyclization reactions, enabling diverse chemical transformations. It exhibits good solubility in common organic solvents, supporting homogeneous reaction conditions and reproducible results. The compound's stability under standard storage conditions ensures reliable performance in both laboratory and industrial-scale synthesis. Additionally, its versatility and predictable reactivity make it a convenient and efficient building block for multi-step synthetic strategies.

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Conclusion

Diethyl 2-(2-cyanoethyl)malonate is a valuable intermediate for the synthesis of heterocycles, pharmaceuticals, and fine chemicals. Its applications in carbon–carbon bond formation and functionalized molecule construction, combined with benefits such as stability, versatility, and reproducible reactivity, make it an important compound for chemical research and industrial production. The compound continues to support efficient and flexible organic synthesis pathways.

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