1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone
CAS 1267610-26-3
CAS · 1267610-26-3
Product Overview
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Pale yellow to off-white powder |
|---|---|
| Purity (HPLC) | 98% min |
| Any other individual impurity | 0.2% max |
Applications
1-(4-Aminophenyl)-5,6-dihydro-3-(4-morpholinyl)-2(1H)-pyridinone is primarily used as a synthetic intermediate in pharmaceutical and medicinal chemistry research. It serves as a valuable scaffold for the development of small-molecule drug candidates, particularly in areas such as oncology, inflammation, and central nervous system research. The compound's heterocyclic core and functional substituents make it suitable for further derivatization to generate libraries of analogues for structure–activity relationship studies. It is also applied in biochemical research to explore enzyme inhibition, receptor binding, and signaling pathway modulation. Additionally, the compound is used in advanced organic synthesis for constructing nitrogen-containing heterocycles and complex bioactive molecules.
Benefits
This compound offers several advantages due to its multifunctional and pharmacologically relevant structure. The dihydropyridinone core provides a stable yet modifiable framework that supports diverse chemical transformations. The presence of an aminophenyl group enables further functionalization and potential interactions with biological targets, while the morpholine moiety enhances solubility and improves physicochemical properties such as polarity and bioavailability in derived compounds. Its well-defined structure supports reproducibility and selectivity in synthetic and medicinal chemistry workflows. Furthermore, the compound is compatible with standard coupling and modification reactions, facilitating efficient lead optimization and molecular design.
Conclusion
1-(4-Aminophenyl)-5,6-dihydro-3-(4-morpholinyl)-2(1H)-pyridinone is a versatile intermediate with significant value in pharmaceutical research and heterocyclic chemistry. Its applications in drug discovery and molecular optimization, combined with benefits such as structural versatility, favorable physicochemical characteristics, and synthetic reliability, make it an important building block in modern medicinal chemistry. The compound continues to support the development of innovative bioactive molecules and advanced therapeutic research.
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