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Product Line: Pharmaceutical Chemicals

Chlorhexidine hydrochloride

CAS 3697-42-5

Molecular structure of Chlorhexidine hydrochloride

CAS · 3697-42-5

01

Product Overview

Chlorhexidine hydrochloride is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance White or almost white crystalline powder, odorless, bitter taste
Content 98.0% min
Solubility Very slightly dissolved in water or ethanol
Melting point Simultaneous decomposition at 255 to 259°C
Identification (1) Comply with positive reaction
(2) Comply with positive reaction
(3) Maximum absorption occurs at 258nm wavelength
(4) Comply with positive reaction
Check: p-chloroaniline Comply with regulations
Loss on drying 1.0% max
Residue on ignition 0.1% max
03

Applications

Chlorhexidine hydrochloride is a broad-spectrum antiseptic and disinfectant widely used in healthcare, personal care, and industrial applications. In medical and dental settings, it is applied as a topical antiseptic for preoperative skin preparation, wound care, and oral rinses to prevent bacterial infections and maintain oral hygiene. It is commonly incorporated into mouthwashes, toothpaste, and periodontal treatment products to reduce plaque, gingivitis, and oral microbial load. Beyond healthcare, chlorhexidine hydrochloride is used in disinfectants for surgical instruments, medical devices, and hospital surfaces, as well as in personal care products such as soaps, lotions, and wipes. Its antimicrobial efficacy against Gram-positive and Gram-negative bacteria, yeasts, and some viruses makes it a versatile and reliable antiseptic agent.

04

Benefits

The benefits of chlorhexidine hydrochloride stem from its broad-spectrum antimicrobial activity, rapid action, and sustained residual effect. It effectively kills bacteria and inhibits microbial growth on skin, mucous membranes, and surfaces, helping to prevent infections and cross-contamination. In oral care, it reduces plaque formation and gingival inflammation, improving oral health over time. Its residual activity ensures prolonged protection even after initial application, making it particularly valuable in healthcare and hygiene settings. Additionally, chlorhexidine hydrochloride is relatively stable, water-soluble, and compatible with various formulations, allowing its use in solutions, gels, creams, and impregnated materials. Its safety profile, when used appropriately, further supports its widespread use in both medical and consumer products.

05

Conclusion

Chlorhexidine hydrochloride is a highly effective antiseptic with broad applications in medical, dental, and personal care industries. Its ability to rapidly eliminate microbes, provide prolonged antimicrobial protection, and integrate into diverse formulations makes it an essential component for infection control, oral health, and hygiene. The benefits it delivers-broad-spectrum efficacy, residual activity, and formulation versatility-underscore its continued importance in healthcare, personal care, and industrial disinfection applications.

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