CAS · 2897-43-0
Product Overview
4-Amino-2,6-dichloro-3-nitropyridine is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Light yellow powder |
|---|---|
| Purity | 98% min |
| Melting Point (MP) | 148~150 °C |
Applications
4-Amino-2,6-dichloro-3-nitropyridine is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty heterocyclic compounds. Its structure, featuring an amino group, two chloro substituents, and a nitro group on the pyridine ring, allows for selective substitution, reduction, and coupling reactions, making it suitable for constructing complex nitrogen-containing heterocycles. The compound is employed in the preparation of herbicides, fungicides, and other agrochemical agents where pyridine derivatives provide stability and bioactivity. It is also used in medicinal chemistry for synthesizing intermediates in drug discovery, including compounds that target enzymes or receptors with pyridine-based scaffolds, as well as in research laboratories studying functionalized heterocyclic systems.
Benefits
The benefits of 4-Amino-2,6-dichloro-3-nitropyridine arise from its multifunctional structure, which allows for diverse chemical transformations while maintaining reactivity control. The dichloro substitution facilitates selective nucleophilic substitution reactions, enabling targeted functionalization at specific positions on the ring. The amino and nitro groups provide handles for further derivatization, including reduction, acylation, and condensation reactions, expanding the scope of accessible derivatives. Its stability under standard laboratory conditions and predictable reactivity profile make it convenient for multi-step synthesis, improving efficiency and yield while minimizing unwanted side reactions. These properties make it a reliable building block for complex organic synthesis in both industrial and research applications.
Conclusion
4-Amino-2,6-dichloro-3-nitropyridine is a valuable intermediate for the synthesis of pharmaceuticals, agrochemicals, and heterocyclic compounds. Its applications in constructing functionalized pyridine derivatives, along with benefits such as chemical versatility, stability, and predictable reactivity, make it an important tool for organic synthesis. The compound supports efficient production of advanced molecules and enables the development of bioactive and functional chemical entities.
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