3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride
CAS 5409-58-5
CAS · 5409-58-5
Product Overview
3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Description: | Off-White to white powder |
|---|---|
| Purity (HPLC): | 99% min |
| Identification: | By HPLC: The retention time of the main peak obtained from the sample is same as the reference sample |
| Loss on Drying: | 1.0% max |
| Water: | 1% max |
| Single Max Impurity: | 0.5% max |
| Total Impurities: | 1% max |
Applications
3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride is a highly versatile organic intermediate widely used in pharmaceutical synthesis, medicinal chemistry, and chemical research. It serves as a key building block for the synthesis of substituted naphthyl ketones, amines, and heterocyclic compounds. In pharmaceutical research, it is used to prepare molecules with potential analgesic, CNS-active, or therapeutic properties, allowing chemists to explore structure-activity relationships (SAR) and optimize pharmacological activity. The compound's reactive ketone and tertiary amine groups make it suitable for condensation, reductive amination, and alkylation reactions, enabling the construction of more complex organic molecules. Additionally, it is utilized in fine chemical production and academic research as a starting material for the development of novel bioactive compounds and intermediates in organic synthesis.
Benefits
The benefits of this compound arise from its structural versatility, reactivity, and stability. The naphthyl ketone provides a rigid aromatic backbone for molecular design, while the dimethylamino group enhances solubility and offers a nucleophilic site for functionalization. The hydrochloride salt form improves stability, crystallinity, and handling, making it convenient for storage and precise dosing in laboratory applications. Its dual functional groups allow for efficient downstream reactions, reducing synthesis steps and improving overall yield. Moreover, its well-characterized chemical properties facilitate reproducible experimental results, supporting research in drug discovery and organic synthesis. Its combination of reactivity, stability, and structural flexibility makes it an essential intermediate for both industrial and academic chemistry applications.
Conclusion
3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride (CAS 5409-58-5) is a valuable organic intermediate for pharmaceutical synthesis and chemical research. Its reactive ketone and tertiary amine functionalities, coupled with a stable naphthyl framework, provide chemists with a versatile building block for constructing bioactive molecules and advanced organic compounds. By enabling efficient, high-fidelity synthesis, it plays a crucial role in medicinal chemistry, fine chemical production, and innovative organic synthesis.
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