CAS · 72287-77-5
Product Overview
2-amino-N,N-dimethylacetamide hydrochloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Off-white to white powder |
|---|---|
| Identification: | GC spectrum of sample corresponds to that of standard preparation 1H NMR spectrum of sample corresponds to that of standard preparation |
| Purity (GC): | 98% min |
| Related substances: | Single impurity: 1.0% max Total impurities: 2.0% max |
Applications
This compound is primarily used as a synthetic intermediate in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. It serves as a building block for amide- or amine-containing bioactive molecules, including enzyme inhibitors, CNS-active agents, and receptor modulators. The dimethylamino functionality allows for further chemical transformations, such as alkylation, acylation, or cyclization, to generate more complex heterocycles or substituted derivatives. In medicinal chemistry, it is employed for designing drug candidates with improved solubility and metabolic stability. Additionally, it is used in chemical research for studying structure-activity relationships and in organic synthesis as a reagent or intermediate for constructing nitrogen-containing scaffolds.
Benefits
The benefits of 2-amino-N,N-dimethylacetamide hydrochloride include its chemical versatility, stability, and solubility. The dimethylated amine group enables diverse reactions and derivatization, while the hydrochloride salt improves shelf-life and handling safety. The compound is highly soluble in water and common organic solvents, making it compatible with various synthetic protocols. Its small size and simple structure allow easy incorporation into multi-step syntheses without introducing steric hindrance, while maintaining reactivity and functional integrity throughout reaction sequences.
Conclusion
In summary, 2-amino-N,N-dimethylacetamide hydrochloride is a versatile amide intermediate used in pharmaceutical synthesis, organic chemistry, and fine chemical production. Its dimethylamino functionality and hydrochloride form provide chemical adaptability, solubility, and stability, making it ideal for constructing bioactive molecules and nitrogen-containing scaffolds. With its reliability, reactivity, and ease of handling, it serves as a valuable building block for drug development and complex organic synthesis.
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