CAS · 53801-63-1
Product Overview
Zinc-Copper-couple is a high-purity analytical-reagents supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | grey to black Powder |
|---|---|
| Assay: | 1-3% |
| Odor: | characteristic |
| Loss weight: | 0.3% max |
Applications
1. Organic Synthesis Catalyst
Zinc-copper couple is extensively used to promote a variety of reactions, including:
Reductive dehalogenation
Synthesis of organozinc reagents
Coupling reactions
Preparation of vinyl and alkyl zinc compounds for further functionalization
2. Preparation of Alkyl and Aryl Zinc Reagents
In situ formation of organozinc compounds using zinc-copper couple facilitates the synthesis of compounds via Negishi coupling and other cross-coupling methodologies.
3. Reduction Reactions
Used as a mild and selective reducing agent, zinc-copper couple enables reductions of halides, nitro groups, and other functional groups without harsh conditions.
4. Cyclopropanation and Ring-Forming Reactions
Employed in the synthesis of cyclopropane derivatives and other ring systems via carbenoid or organozinc intermediates.
5. Industrial Chemical Processes
Used in fine chemical manufacturing for intermediates in pharmaceuticals, agrochemicals, and specialty chemicals.
Benefits
Enhanced Reactivity: The presence of copper enhances the surface activity and electron transfer capability of zinc.
Selective Reductions: Allows for milder and more controlled reaction conditions compared to pure zinc.
Versatility: Applicable in a wide range of synthetic transformations.
Improved Handling: Generally safer and easier to handle than other reactive metals or reducing agents.
Cost-Effective: Economical reagent for large-scale organic synthesis.
Conclusion
Zinc-Copper Couple (CAS 53801-63-1) is a valuable reagent in organic chemistry, combining the reducing power of zinc with the catalytic benefits of copper. Its ability to facilitate selective reductions, organozinc formation, and coupling reactions makes it indispensable in both academic and industrial synthesis. The zinc-copper couple continues to enable efficient and practical routes to complex molecules in pharmaceuticals, agrochemicals, and fine chemicals.
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