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3-N,N-Dimethylaminopropylmagnesium Chloride

CAS 154034-91-0

Molecular structure of 3-N,N-Dimethylaminopropylmagnesium Chloride

CAS · 154034-91-0

01

Product Overview

3-N,N-Dimethylaminopropylmagnesium Chloride is a high-purity grignard-reagent supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance Colorless to brown liquid
Titration 0.90 ~ 1.10 M
03

Applications

3-N,N-Dimethylaminopropylmagnesium chloride is primarily used as a Grignard reagent in organic synthesis. It serves as a nucleophilic source of the 3-(dimethylamino)propyl group, enabling the formation of carbon–carbon bonds in the preparation of amine-functionalized molecules. This compound is particularly useful in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals where introduction of a tertiary amine functionality is required. It can also be employed in the preparation of quaternary ammonium salts, intermediates for surfactants, and ligands for organometallic catalysis. Its reactivity under controlled conditions allows selective functionalization of electrophilic centers, supporting complex molecular construction in research and industrial applications.

04

Benefits

The benefits of 3-N,N-Dimethylaminopropylmagnesium chloride include its high reactivity and versatility as a nucleophilic organometallic reagent. Its Grignard character allows efficient introduction of the 3-(dimethylamino)propyl moiety into a variety of electrophilic substrates, facilitating the synthesis of amine-containing compounds. The compound provides predictable and controllable reactivity under anhydrous conditions, enabling selective transformations with minimal by-product formation. Its functionality and stability in properly handled conditions support reproducible reactions, reduce synthesis steps, and enhance the overall efficiency of complex molecule preparation, making it a valuable tool for synthetic chemists.

05

Conclusion

3-N,N-Dimethylaminopropylmagnesium chloride is a versatile Grignard reagent widely used in the synthesis of pharmaceuticals, agrochemicals, and functional organic intermediates. Its reactivity, selectivity, and ability to introduce tertiary amine groups make it an important building block in complex molecular construction. These properties provide efficiency, reliability, and flexibility in both research and industrial chemical synthesis.

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