tert-Butyl (2-(2-(2-bromoethoxy)ethoxy)ethyl)carbamate

tert-Butyl (2-(2-(2-bromoethoxy)ethoxy)ethyl)carbamate is a high-purity polyethylene-glycol supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

tert-Butyl (2-(2-(2-bromoethoxy)ethoxy)ethyl)carbamate is a versatile intermediate widely used in organic synthesis, medicinal chemistry, and bioconjugation. Its protected amine group (Boc) allows selective reactions at the bromoalkyl terminus while preventing unwanted N-alkylation, making it suitable for multi-step synthetic routes. The terminal bromide can undergo nucleophilic substitution or coupling reactions to attach the molecule to nucleophiles, azides, or other functional groups, enabling the synthesis of PEGylated compounds, drug conjugates, and functional linkers. This intermediate is particularly valuable in the design of PEG-based linkers, prodrugs, and modified peptides, where the Boc protection provides stability and selectivity during synthesis.

The benefits of this compound stem from its combination of reactivity, stability, and functional versatility. The Boc-protected amine ensures inertness under a wide range of reaction conditions, allowing selective functionalization of the bromoalkyl group. The triethylene glycol backbone provides water solubility, flexibility, and reduced steric hindrance, which is valuable in conjugation and drug delivery applications. Its terminal bromide enables efficient nucleophilic substitution reactions, facilitating the introduction of diverse functional groups. Together, these features provide predictable reactivity, enhanced solubility, and compatibility with multi-step synthetic protocols.

tert-Butyl (2-(2-(2-bromoethoxy)ethoxy)ethyl)carbamate is a valuable intermediate for organic synthesis, PEGylation, and drug conjugation. Its combination of Boc-protected amine, reactive bromo group, and hydrophilic linker backbone allows selective, efficient, and versatile molecular modifications. By enabling controlled functionalization and conjugation, it serves as an essential building block in medicinal chemistry, bioconjugation, and materials research.

Previous

Dodecaethylene Glycol丨CAS 6790-09-6

Next

3,6,9,12-Tetraoxatridecylamine丨CAS 85030-56-4