CAS · 1177-87-3
Product Overview
Dexamethasone-17-acetate is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade: | USP 42 |
|---|---|
| Appearance: | White or almost white crystalline powder |
| Identification (IR, UV): | Complies with the standard |
| Specific Rotation: | +82 ~ +88° |
| Residue on ignition: | 0.1% max |
| Loss on drying: | 0.4% max |
| Heavy Metals: | 20 ppm max |
| Chromatographic purity: | |
| Individual Impurity: | 1.0% max |
| Total Impurity: | 2.0% max |
| Assay: | 97.0% - 102.0% |
| Residual solvents: | |
| Acetone: | 1000 ppm max |
Applications
1. Pharmaceutical Industry
Used as an active pharmaceutical ingredient (API) or intermediate in the production of topical, injectable, or oral corticosteroid medications.
Employed in formulations to treat conditions such as asthma, rheumatoid arthritis, allergic reactions, and dermatological inflammations.
The acetate ester form can enhance the drug's absorption and bioavailability in certain delivery routes.
2. Research & Development
Utilized in biochemical and pharmacological studies focused on corticosteroid mechanisms, receptor interactions, and anti-inflammatory effects.
Acts as a reference standard or starting material for synthesizing related corticosteroid derivatives.
Benefits
✔️ Potent Anti-inflammatory Activity
Exhibits strong glucocorticoid effects, effectively reducing inflammation and suppressing immune responses.
✔️ Improved Stability
The acetate ester enhances chemical stability compared to free dexamethasone, beneficial for longer shelf life and controlled release.
✔️ Versatile Formulation Options
Suitable for incorporation into various pharmaceutical forms, including creams, ointments, injectables, and tablets.
Conclusion
Dexamethasone-17-acetate is a valuable corticosteroid derivative widely used in pharmaceutical formulations for its potent anti-inflammatory and immunosuppressive effects. Its enhanced stability and versatility make it a preferred choice in the design of topical and systemic corticosteroid therapies.
Previous
Fluocinolone Acetonide丨CAS 67-73-2
Next