CAS · 547-32-0
Product Overview
Sodium sulfadiazine is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Item | Specification |
|---|---|
| Grade | USP43 |
| Appearance | White or almost white crystalline or powder |
| Assay (calculated on the dried basis) | 99% to 100.5% |
| Identification A | The infrared absorption spectrum concordant with the spectrum of sulfadiazine CRS |
| Identification B | Test for sodium |
| Solubility | Freely soluble in water, slightly soluble in alcohol |
| Heavy Metals | 10 ppm max |
| Melting Range | 250°C to 254°C |
| Clarity of the Solution | Clear |
| pH | 9.6 to 10.5 |
| Selenium | 30 ppm max |
| Loss on Drying | 0.5% max |
Applications
1. Human Medicine
a. Antibacterial Agent
● Sodium sulfadiazine丨CAS 547-32-0 is effective against a wide range of Gram-positive and Gram-negative bacteria, especially Streptococcus, E. coli, and some strains of Haemophilus.
● Often used in urinary tract infections, respiratory infections, and toxoplasmosis when combined with pyrimethamine.
b. Alternative to Silver Sulfadiazine
● In certain formulations, sodium sulfadiazine may be used where silver-based creams are contraindicated.
● Also explored in systemic infections requiring soluble sulfonamide forms.
2. Veterinary Medicine
● Used to treat bacterial infections in livestock (e.g., pigs, cattle, poultry) and companion animals.
● Often included in feed additives or injectable solutions for treating enteritis, pneumonia, and wound infections in animals.
3. Pharmaceutical Formulations
● Acts as an active pharmaceutical ingredient (API) in the production of:
Injectable antibiotics
Oral sulfonamide tablets
Eye drops and topical antimicrobial preparations
Benefits
√ Broad-Spectrum Antibacterial Activity
● Effective against a wide variety of bacterial pathogens by inhibiting folic acid synthesis, an essential process in bacterial metabolism.
√ Water-Soluble Salt Form
● The sodium salt improves bioavailability and allows parenteral (injectable) administration, particularly in patients who cannot take oral medication.
√ Useful in Combination Therapy
● Used with pyrimethamine to treat toxoplasmosis and malaria, taking advantage of synergistic inhibition of microbial folate pathways.
√ Cost-Effective and Widely Available
● Generic and affordable, making it a staple antibiotic in resource-limited settings or veterinary practices.
√ Veterinary and Agricultural Uses
● Helps maintain livestock health and prevent economic losses due to bacterial outbreaks in animal farming.
Conclusion
Sodium sulfadiazine丨CAS 547-32-0 is a potent sulfonamide antibiotic valued for its water solubility, broad-spectrum activity, and effectiveness in systemic and topical applications. It remains a useful and cost-effective solution for both human and veterinary medicine, particularly in treating bacterial infections and protozoal diseases such as toxoplasmosis.
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Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.