CAS · 751-94-0
Product Overview
Sodium fusidate is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Characteristics: | White or off white crystalline powder |
|---|---|
| Content: | 97.5%–101.0% |
| Solubility: | Soluble in water, ethanol; slightly wetting |
| Identification: | IR Complies |
| pH: | 7.5–9.0 |
| Water: | 2.0% max |
| Impurities: | M: 1.0% max G: 0.7% max L: 0.5% max B: 0.4% max A: 0.3% max H: 0.1% max C: 0.2% max D: 0.2% max F: 0.2% max I: 0.2% max K: 0.2% max N: 0.2% max Unspecified impurities: 0.10% max Total impurities: 2.0% max |
Applications
Sodium fusidate (CAS 751-94-0) is a sodium salt form of fusidic acid, widely used as an antibiotic in both human and veterinary medicine. It is primarily applied in topical formulations such as creams, ointments, and eye drops to treat skin infections, wound infections, and ocular bacterial infections caused by Gram-positive bacteria, particularly Staphylococcus aureus. It is also available in oral and injectable forms for systemic infections, including bone and joint infections, respiratory tract infections, and sepsis. Sodium fusidate is often included in combination therapies to enhance efficacy against resistant bacterial strains.
Benefits
The benefits of sodium fusidate arise from its potent antibacterial activity, low toxicity, and targeted mechanism of action. It inhibits bacterial protein synthesis by interfering with elongation factor G (EF-G), which provides selective bacteriostatic or bactericidal effects against susceptible Gram-positive bacteria. Its sodium salt form enhances water solubility and stability, making it suitable for a variety of pharmaceutical formulations. Additionally, sodium fusidate has a favorable safety profile, minimal systemic absorption in topical use, and low incidence of adverse effects, which makes it a reliable choice for both acute and chronic bacterial infections.
Conclusion
Sodium fusidate is an effective antibiotic with broad applications in topical, oral, and injectable formulations for treating Gram-positive bacterial infections. Its potent activity, solubility, stability, and safety profile make it a valuable agent in both clinical and veterinary settings. By providing targeted antibacterial action and formulation versatility, sodium fusidate remains an essential compound in antimicrobial therapy.
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