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Product Line: Pharmaceutical Chemicals

beta-Cyclodextrin hydrate

CAS 68168-23-0

CAS · 68168-23-0

01

Product Overview

beta-Cyclodextrin hydrate is a high-purity cyclodextrin-derivatives supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Grade: USP25
Appearance: White crystalline powder
Assay: 98% to 101%
Specific rotation: (+159) to (+164) °
Moisture: 14% max
As: 0.002% max
Residue on ignition: 0.1% max
Heavy metals: 10 ppm max
Glucose: 1.0% max
pH: 5.0 to 8.0
Residue sugars: 0.1% max
Total Plate Count (T.P.C): 1000 /g max
Molds and yeasts: 100 /g max
Escherichia coli: Negative
03

Applications

1. Pharmaceutical Industry

Drug Solubilization: Enhances solubility and bioavailability of hydrophobic drugs by encapsulating them in its cavity.

Stabilization of APIs: Protects active pharmaceutical ingredients (APIs) from hydrolysis, oxidation, and photodegradation.

Controlled Drug Delivery: Allows for sustained and targeted drug release, reducing side effects.

Taste and Odor Masking: Masks unpleasant tastes or odors of oral drug formulations.

2. Food and Beverage Industry

Flavor and Aroma Retention: Encapsulates volatile compounds, preventing degradation during storage and processing.

Cholesterol Reduction: Removes cholesterol from dairy products (e.g., milk, butter, eggs) without affecting texture or taste.

Encapsulation of Nutrients: Stabilizes and delivers sensitive compounds like vitamins and antioxidants.

3. Cosmetics and Personal Care

Fragrance Stabilization: Controls release and longevity of fragrances in perfumes, lotions, and sprays.

Skin Care Formulations: Helps deliver active ingredients like retinoids or peptides in a stable, non-irritating form.

Reduction of Greasiness: Provides a dry, silky feel to formulations with oily ingredients.

4. Industrial and Environmental Applications

Catalysis Support: Used in green chemistry for selective catalysis and enzyme immobilization.

Pollutant Removal: Binds hydrophobic organic pollutants in aqueous environments for water purification.

Textile and Packaging: Incorporated into smart materials for slow release of functional agents (e.g., antimicrobials, fragrances).

04

Benefits

Feature

Benefit

Hydrophilic exterior & hydrophobic cavity

Forms inclusion complexes with various guest molecules

High aqueous solubility (compared to other CDs)

Effective in water-based applications

Biodegradable & Non-toxic

Safe for pharmaceutical, food, and cosmetic use

GRAS status (generally recognized as safe)

Approved by FDA and EFSA for specific uses

Versatility

Used across pharmaceuticals, food, cosmetics, and industry

05

Conclusion

beta-Cyclodextrin hydrate丨CAS 68168-23-0 is a safe, multifunctional excipient widely used for improving solubility, stability, and delivery of hydrophobic substances in pharmaceuticals, foods, cosmetics, and environmental systems. Its ability to form inclusion complexes and its biodegradable nature make it a valuable tool for both research and industrial-scale applications.

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