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Product Line: Pharmaceutical Chemicals

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol

CAS 22323-82-6

Molecular structure of (S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol

CAS · 22323-82-6

01

Product Overview

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance: Colorless transparent liquid
Purity (GC): 98.0% min
Water (K.F.): 0.5% max
Optical rotation: 13.5° ± 1.0°
03

Applications

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol is a chiral building block widely used in pharmaceutical and fine chemical synthesis. Its enantiomerically pure structure makes it valuable for the synthesis of optically active compounds, including antiviral, anticancer, and CNS-active drug candidates. The dioxolane ring provides a protected diol functionality, allowing selective reactions at the methanol group without affecting other sensitive sites. It is also employed in asymmetric synthesis, as a chiral auxiliary or intermediate, facilitating the preparation of complex molecules with high stereoselectivity. Additionally, it is used in chemical research for the development of novel heterocycles and as a precursor for functionalized intermediates in organic synthesis.

04

Benefits

The compound offers high stereochemical purity and chemical stability, enabling precise control over reaction outcomes in multi-step syntheses. Its protected diol structure provides versatility for selective transformations, such as oxidation, esterification, or nucleophilic substitution, while minimizing side reactions. The presence of the chiral center allows the efficient generation of enantiomerically enriched products, which is critical in drug development and fine chemical synthesis. Its solubility in common organic solvents and compatibility with a variety of reaction conditions further enhance its practical utility in laboratory and industrial applications.

05

Conclusion

(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol is a valuable chiral intermediate for pharmaceutical and fine chemical synthesis. Its stereochemical purity, chemical stability, and functional versatility make it an essential building block for the preparation of optically active molecules and complex intermediates, supporting the development of high-value drugs and advanced chemical products.

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