CAS · 4254-15-3
Product Overview
(S)-(+)-1,2-Propanediol is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Colorless transparent liquid |
|---|---|
| Purity (GC) | 99.5% min |
| Water (KF) | 0.3% max |
| Identification by GC | The retention time of test sample should match with retention time of standard |
| Bis (2-hydroxypropyl) ether | 0.1% max |
| Propylene Oxide | 413 ppm max |
| Single Maximum Unspecified Impurity | 0.1% max |
| Total Impurities | 0.5% max |
| R-(-)-1,2-Propanediol | 1.0% max |
| Peroxide Content | 3 ppm max |
Applications
(S)-(+)-1,2-Propanediol is a chiral diol widely used as a building block in pharmaceutical, chemical, and polymer industries. It serves as a key intermediate in the synthesis of enantiomerically pure compounds, including chiral solvents, active pharmaceutical ingredients (APIs), and specialty chemicals. In medicinal chemistry, it is employed for the production of beta-blockers, antifreeze agents, and other stereochemically sensitive drugs. Its hydroxyl groups also allow its application in polymer synthesis, including polyesters, polyurethanes, and epoxy resins, where it contributes to enhanced flexibility and functionality. Additionally, it is used in the formulation of cosmetics, food additives, and as a solvent in various industrial processes.
Benefits
The benefits of (S)-(+)-1,2-propanediol stem from its chirality, high purity, and multifunctional reactivity. Its (S)-configuration enables the production of stereochemically defined compounds, which is essential for pharmaceuticals requiring specific enantiomers for efficacy and safety. Its two hydroxyl groups provide versatile chemical reactivity for esterification, etherification, and polymerization reactions. The compound is water-soluble, stable under standard conditions, and compatible with a variety of solvents and reaction conditions, making it convenient for laboratory and industrial synthesis. These properties allow efficient, reproducible, and scalable production of target molecules across multiple sectors.
Conclusion
In summary, (S)-(+)-1,2-propanediol is a chiral diol with applications in pharmaceuticals, polymer synthesis, chemical intermediates, and industrial formulations. Its benefits include enantiomeric purity, multifunctional reactivity, chemical stability, and versatility in synthetic applications. By combining stereochemical precision with practical utility, (S)-(+)-1,2-propanediol continues to be an important intermediate in advanced chemical and pharmaceutical synthesis.
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