CAS · 1501-84-4
Product Overview
Rimantadine hydrochloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Deep yellow liquid |
|---|---|
| Purity (HPLC) | 97% min |
| Identification (HPLC) | Conforms |
| Identification (1H-NMR) | Conforms |
Applications
Rimantadine hydrochloride (CAS 1501-84-4) is a well-established antiviral compound primarily used in the prevention and treatment of influenza A virus infections. It functions as an M2 ion channel inhibitor, blocking viral uncoating and replication within host cells. Beyond its medical applications, Rimantadine hydrochloride is also employed in pharmaceutical research as a reference standard, a lead compound for developing improved antivirals, and in structural activity relationship (SAR) studies. In addition, it has been investigated for potential activity against other viral pathogens and explored in materials science for its rigid adamantane scaffold, which provides unique properties in the design of functionalized derivatives.
Benefits
The key benefits of Rimantadine hydrochloride include its proven clinical efficacy in reducing influenza A symptoms and duration when administered promptly, as well as its prophylactic effectiveness in preventing infection during seasonal influenza outbreaks. Compared with its analogue amantadine, rimantadine generally exhibits fewer central nervous system (CNS) side effects due to its altered pharmacokinetics, improving patient tolerability. Its adamantane-based structure provides metabolic stability and lipophilicity, enhancing oral bioavailability. In research contexts, the compound serves as a reliable scaffold for drug design, offering opportunities to develop next-generation antivirals with reduced resistance profiles.
Conclusion
In summary, Rimantadine hydrochloride is a clinically important antiviral agent with primary use against influenza A, while also serving as a valuable tool in pharmaceutical development. Its benefits include strong antiviral efficacy, improved tolerability compared with similar drugs, and a versatile adamantane framework suitable for molecular innovation. Despite the emergence of resistant viral strains, Rimantadine hydrochloride remains an important reference compound in virology, medicinal chemistry, and antiviral research.
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