CAS · 36322-90-4
Product Overview
Piroxicam is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade | USP42 |
|---|---|
| Appearance | Off-white to light tan or light yellow, odorless powder; from a monohydrate that is yellow |
| Identification - IR | Similar to the reference standard |
| Identification - TLC | Similar to the reference standard |
| Identification - UV | Maximum absorption at the wavelength of 243–334 nm |
| Water | 0.5% max |
| Heavy metals | 0.005% max |
| Residue on ignition | 0.3% max |
| Assay (HPLC) | 97.0%–103.0% |
Applications
Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) widely used in pharmaceuticals for the management of pain, inflammation, and arthritis-related conditions. It is commonly formulated for oral administration in tablets, capsules, or liquid suspensions, and in some cases as topical gels or creams for localized relief. Piroxicam is particularly effective in treating osteoarthritis, rheumatoid arthritis, and musculoskeletal pain due to its ability to inhibit cyclooxygenase (COX) enzymes, which reduces prostaglandin synthesis and inflammation. Beyond its clinical use, Piroxicam is employed in pharmaceutical research as a reference compound for studying NSAID mechanisms, pharmacokinetics, drug interactions, and formulation development. Its well-characterized structure and bioactivity make it a standard model in medicinal chemistry studies targeting inflammation pathways.
Benefits
The benefits of Piroxicam stem from its long half-life, potent anti-inflammatory action, and analgesic properties. Its extended duration of action allows for once-daily dosing in many formulations, improving patient compliance and convenience. Piroxicam is effective in both acute and chronic inflammatory conditions, providing significant pain relief and reduction of swelling. Its chemical stability ensures reliable performance in various dosage forms, and it is compatible with standard pharmaceutical excipients for tablets, capsules, and topical formulations. Additionally, its well-understood pharmacological profile allows for predictable therapeutic outcomes, making it a preferred NSAID for chronic treatment and clinical research purposes.
Conclusion
Piroxicam is a potent and long-acting NSAID widely used for the treatment of pain and inflammation associated with arthritis and musculoskeletal conditions. Its effectiveness, extended duration of action, and chemical stability make it suitable for diverse pharmaceutical formulations and clinical applications. By providing reliable anti-inflammatory and analgesic effects, Piroxicam remains an essential compound in modern medicine and pharmaceutical research, supporting both therapeutic use and drug development studies.
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