PIPES disodium salt

PIPES disodium salt is a high-purity biological-buffer supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

1. Biological Buffer

PIPES disodium salt is widely used in biological and biochemical research as a Good's buffer, particularly when a stable pH near neutrality is required.

Common uses include:

Cell and tissue culture media

Enzyme assays

Protein purification workflows

Electrophoresis and Western blotting

2. Molecular Biology and Biochemistry

Ideal for buffering solutions used in:

DNA/RNA extraction and hybridization

PCR and other enzyme-based reactions

Biochemical assay development

3. Pharmaceutical and Diagnostic Formulations

Utilized in formulations of biologics, drug delivery systems, and in vitro diagnostic kits where pH stability is critical.

✅ Near-Neutral pH Buffering

pKa of ~6.76 ensures reliable buffering within the physiological range, suitable for sensitive biological systems.

✅ Low Metal Ion Binding

Exhibits minimal chelation of metal ions (e.g., Ca²⁺, Mg²⁺), ensuring compatibility with metal-dependent enzymes and cofactors.

✅ Highly Soluble

Freely soluble in water, allowing quick and easy buffer preparation.

✅ Stable and Reproducible

Chemically stable across a range of temperatures and concentrations, offering consistent results.

✅ UV Transparent

Very low UV absorbance at 260–280 nm, making it ideal for spectrophotometric assays involving proteins or nucleic acids.

PIPES disodium salt (CAS 76836-02-7) is a widely trusted zwitterionic buffer designed for pH control in the slightly acidic to neutral range. Its excellent solubility, stability, and compatibility with biological systems make it indispensable in life sciences, diagnostics, pharmaceuticals, and molecular biology, where precise and interference-free buffering is essential.

Previous

PIPES Monosodium Salt丨CAS 10010-67-0

Next

PIPES Dipotassium Salt丨CAS 108321-27-3