Piperazine-N,N-bis(2-hydroxypropanesulphonic acid) disodium salt
CAS 108321-07-9
CAS · 108321-07-9
Product Overview
Piperazine-N,N-bis(2-hydroxypropanesulphonic acid) disodium salt is a high-purity biological-buffer supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White powder |
|---|---|
| Assay | 99% min. |
| Loss on drying | 1% max. |
| pH (1% aqueous) | 9.7 - 10.3 |
| Solubility (10% aqueous) | Colorless clear |
| Heavy metal (Pb) | 5 ppm max. |
| Ultraviolet absorbance / 260nm (0.1M aq.) | 0.06 max. |
| Ultraviolet absorbance / 280nm (0.1M aq.) | 0.04 max. |
Applications
1. Biological Buffering Agent
POPSO is a member of Good's buffers family, widely used for pH stabilization in biological and biochemical experiments.
Utilized in:
Cell culture media
Protein purification
Enzyme assays
Electrophoresis and chromatographic separations
2. Pharmaceutical Formulations
Applied as a buffer in drug formulations where maintaining pH close to physiological conditions is crucial.
3. Diagnostic and Analytical Reagents
Incorporated into clinical diagnostic kits and reagents requiring stable pH for accurate results.
Benefits
1. Effective Buffering Near Neutral pH
POPSO buffers efficiently in the pH range of 6.0 to 7.2, making it suitable for many biological processes and assays.
2. Minimal Metal Ion Binding
Exhibits low interaction with metal ions, which is important for reactions that involve metal-dependent enzymes or cofactors.
3. Chemical and Thermal Stability
Stable under various laboratory and storage conditions, ensuring consistent performance over time.
4. High Water Solubility
Easily soluble, facilitating preparation of buffers and solutions.
5. Low UV Absorbance
Does not interfere with UV absorbance-based assays, allowing accurate spectrophotometric measurements.
Conclusion
Piperazine-N,N-bis(2-hydroxypropanesulphonic acid) disodium salt (POPSO, CAS 108321-07-9) is a versatile biological buffer that provides stable pH control near neutrality. Its low metal ion affinity, chemical stability, and high solubility make it an excellent choice for biochemical assays, cell culture, pharmaceutical formulations, and diagnostic applications. POPSO supports reproducible and reliable experimental conditions in both research and industrial settings.
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