CAS · 3105-95-1
Product Overview
Pipecolic acid, (-)- is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White to light yellow powder or massive solid |
|---|---|
| Assay | 98% ~ 102.0% |
| EE | 98% min |
| Solubility | Soluble in water |
| Melting point | 272 ~ 278 °C |
| Loss on drying | 1.0% max |
| Specific rotation | -25.0° ± 2° |
Applications
Metabolic & Diagnostic Tool
Used as a biomarker for metabolic disorders such as hyperpipecolic acidemia, Zellweger syndrome, and certain peroxisomal diseases; its accumulation can signal relevant pathologies.
Neuroscience Research
Acts on the central nervous system by modulating gamma-aminobutyric acid (GABA) binding-especially notable in the presence of barbiturates-making it valuable for studying neurotransmission and receptor interactions.
Pharmaceutical Intermediate
Serves as a chiral and structural scaffold for drug development, particularly for compounds derived from or mimicking lysine metabolism pathways.
Plant Biology & Defense
Participates in systemic acquired resistance signaling in plants, making it useful in studies on plant defense mechanisms and metabolic regulation.
Analytical Standard
Employed in analytical chemistry techniques-such as GC-MS-for quantifying related metabolites and validating assay performance.
Benefits
Biologically Relevant Chirality
Its (S)-configuration aligns with physiological forms, enhancing model relevance in biochemical and pharmacological studies.
Multi-Domain Versatility
With roles in medicine, neuroscience, plant physiology, and analytical chemistry, this compound addresses diverse experimental needs.
High Chemical Purity & Stability
Typically available as a white crystalline solid with high purity, well-suited for reliable lab use and consistent experimental outcomes.
Sensitive Diagnostic Potential
Because its levels shift in specific metabolic disorders, it can be leveraged for sensitive and early detection of underlying conditions.
Conclusion
(–)-Pipecolic acid is a multifunctional, chiral amino acid derivative playing key roles across biomedical, pharmaceutical, plant biology, and analytical chemistry domains. Its physiological relevance, diagnostic potential, and adaptability as a research tool make it a powerful compound for exploring metabolic pathways, neurological functions, plant immunity, and disease diagnostics.
Let me know if you'd like a comparison with its racemic or other enantiomeric forms, or a compact property table for quick reference.
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