CAS · 29601-98-7
Product Overview
N-Benzylhydroxylamine hydrochloride is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Description | White solid |
|---|---|
| Purity (HPLC) | 98% min |
| Loss on drying | 0.5% max |
| Max Single impurity | 1.0% max |
Applications
N-Benzylhydroxylamine hydrochloride (CAS 29601-98-7) is a versatile organic reagent widely used in pharmaceutical synthesis, agrochemical development, and organic chemistry research. It serves as a key intermediate for the preparation of oximes, hydroxamic acids, and N-alkylhydroxylamine derivatives, which are important in medicinal chemistry for creating enzyme inhibitors, antiviral agents, and other bioactive molecules. In organic synthesis, it is employed in selective nucleophilic reactions, reductive aminations, and as a building block for heterocyclic compounds. The hydrochloride salt form improves its stability and handling, making it convenient for laboratory use and industrial-scale reactions. Additionally, it is used in fine chemical production and research to derivatize carbonyl compounds, facilitating the synthesis of novel functionalized molecules.
Benefits
The benefits of N-Benzylhydroxylamine hydrochloride arise from its high reactivity, stability, and versatility. Its hydroxylamine functionality allows for selective reactions with aldehydes and ketones to form oximes, while the benzyl group can be used as a protective moiety or further modified to tune chemical properties. The hydrochloride salt provides enhanced shelf-life and safety compared with the free base, reducing degradation and volatility during storage and handling. Its compatibility with a wide range of solvents and reagents enables efficient multi-step syntheses with good yields and reproducibility. These properties make it a reliable intermediate for pharmaceutical, agrochemical, and fine chemical applications, facilitating the rapid development of target molecules with controlled stereochemistry and functionalization.
Conclusion
N-Benzylhydroxylamine hydrochloride is a valuable organic intermediate for the synthesis of oximes, hydroxamic acids, and bioactive compounds in pharmaceuticals and agrochemicals. Its combination of high reactivity, chemical stability, and handling convenience makes it suitable for both research and industrial-scale applications. By enabling selective and efficient transformations, N-Benzylhydroxylamine hydrochloride continues to be a key building block in modern organic synthesis and the development of functional molecules.
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