CAS · 71119-22-7
Product Overview
MOPS sodium salt is a high-purity biological-buffer supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White crystal powder |
|---|---|
| Assay | 99% to 101% |
| Water | 0.5% max |
| Loss on drying | 1.0% max |
| Melting point (MP) | 277-282 °C |
| Solubility (1M aqueous) | Clear, transparent |
| pH | 10 - 12 |
| Lead (Pb) | 0.0005% max |
| Ultraviolet absorbance / 260nm | 0.1% max |
| Ultraviolet absorbance / 280nm | 0.1% max |
Applications
1. Biological and Biochemical Buffer
MOPS sodium salt is a popular Good's buffer used extensively in biological and biochemical experiments that require stable pH near neutrality.
Common applications include:
Cell culture media
Enzyme activity assays
Protein purification
Nucleic acid electrophoresis
Molecular biology protocols
2. Pharmaceutical Formulations
Used to maintain pH in drug formulations and diagnostic reagents sensitive to pH changes.
3. Electrophoresis
Utilized in electrophoretic separations like PAGE to stabilize pH and ensure consistent biomolecule migration.
Benefits
✅ Effective Buffering Near Neutral pH
With a pKa around 7.20, MOPS sodium salt maintains stable pH conditions ideal for many biological systems.
✅ Low Metal Ion Binding
Exhibits minimal chelation of metal ions, preserving activity of metalloenzymes and cofactors.
✅ High Water Solubility
Readily dissolves in aqueous solutions, facilitating buffer preparation.
✅ Chemical and Thermal Stability
Stable under typical experimental conditions for consistent results.
✅ Low UV Absorbance
Minimal absorbance in UV range, making it compatible with spectrophotometric assays.
Conclusion
MOPS sodium salt (CAS 71119-22-7) is an essential biological buffer widely used to maintain pH stability in the 6.5 to 7.9 range. Its buffering efficiency, stability, and low interference with biological molecules make it indispensable in biochemical research, molecular biology, pharmaceutical, and diagnostic applications.
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