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Product Line: Pharmaceutical Chemicals

Methyl 2-hydroxy-3-nitrobenzoate

CAS 22621-41-6

Molecular structure of Methyl 2-hydroxy-3-nitrobenzoate

CAS · 22621-41-6

01

Product Overview

Methyl 2-hydroxy-3-nitrobenzoate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.

02

Product Specifications

Appearance Light yellow solid powder
1H NMR Spectrum Conforms to structure
Purity (HPLC) 98% min
Water (K.F) 1.0% max
03

Applications

Methyl 2-hydroxy-3-nitrobenzoate is an aromatic ester compound widely used as an intermediate in organic synthesis. It serves as a building block in the production of pharmaceuticals, agrochemicals, dyes, and specialty chemicals. The molecule's hydroxy and nitro functional groups allow selective transformations, making it suitable for reactions such as esterification, reduction, nitration, and substitution. It is commonly used in the synthesis of heterocyclic compounds, analgesic intermediates, and fine chemicals, where its functionalized aromatic ring provides a reactive site for constructing more complex structures. Additionally, it is employed in the preparation of chemical probes, ligands, and intermediates for pharmaceutical research and development, facilitating the study of reaction mechanisms and functional group derivatization. Its stable ester structure combined with reactive substituents makes it versatile for both laboratory and industrial-scale syntheses.

04

Benefits

The compound offers several advantages in chemical synthesis. Its combination of hydroxy and nitro groups provides high reactivity and selectivity, allowing precise modifications of the aromatic ring while maintaining the ester functionality. The methyl ester enhances solubility in organic solvents, simplifying handling, purification, and reaction monitoring. The nitro group can be selectively reduced or further functionalized, enabling the creation of amino derivatives or other substituted aromatic compounds. The hydroxy group also allows for additional derivatization, including protection, esterification, or coupling reactions. Overall, Methyl 2-hydroxy-3-nitrobenzoate provides a balance of stability and chemical reactivity, making it an efficient and reliable intermediate for pharmaceutical, agrochemical, and specialty chemical synthesis.

05

Conclusion

Methyl 2-hydroxy-3-nitrobenzoate is a versatile intermediate in organic synthesis, widely used in the production of pharmaceuticals, agrochemicals, dyes, and specialty chemicals. Its hydroxy and nitro substituents, combined with the methyl ester, provide reactive sites for selective functionalization and complex molecule construction. By offering stability, solubility, and reactivity, it supports efficient, controlled chemical transformations and the scalable production of fine chemicals, making it a valuable tool in both research and industrial applications.

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