CAS · 1599440-25-1
Product Overview
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White to off-white solid |
|---|---|
| Purity (HPLC): | 98% min |
| Total impurities: | 2.0% max |
| Identification by 1H-NMR: | HPLC: the retention time of major peak of sample solution |
Applications
This compound is primarily used in biochemical and pharmaceutical research as a substrate or intermediate in studies of peptide-modifying enzymes such as proteases and peptidases. Its specific sequence (Gly-Gly-Phe-Gly) allows for investigation of enzyme specificity, catalytic efficiency, and substrate interactions. In medicinal chemistry, it can serve as a precursor for the design of peptide-based drugs, prodrugs, or enzyme inhibitors. The functionalized terminal group (NH-CH2-O-CH2COOH) enables conjugation with other molecules, including polymers, fluorescent probes, or drug carriers, facilitating the development of peptide-drug conjugates, targeted delivery systems, or diagnostic tools. Additionally, it is used in peptide synthesis and methodology research to explore functionalization strategies and improve synthetic protocols for peptide derivatives.
Benefits
The benefits of MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH include its defined peptide sequence, functional versatility, and compatibility with conjugation chemistry. The Gly-Gly-Phe-Gly sequence provides a model substrate for enzymatic studies, while the terminal hydroxymethyl carboxylic group allows for selective chemical modifications and coupling reactions. It is stable under standard laboratory conditions and compatible with common peptide synthesis strategies. Its versatility supports the development of targeted peptide conjugates, enzyme assays, and bioactive molecule design. Moreover, the defined stereochemistry and sequence ensure reproducibility in research and synthesis, which is critical for biochemical and pharmaceutical applications.
Conclusion
In summary, MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a functionalized tetrapeptide derivative used in enzymology, peptide-based drug design, and conjugation studies. Its defined sequence, reactive terminal group, and chemical stability make it a valuable tool for investigating enzyme activity, constructing peptide conjugates, and developing bioactive molecules. With its versatility and reproducibility, it supports research and development in biochemical, medicinal, and peptide chemistry applications.
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