CAS · 859-18-7
Product Overview
Lincomycin hydrochloride is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade | CP2015 Grade |
|---|---|
| Appearance | White crystalline powder |
| Identification | Meets the Requirements |
| Crystallinity | Meets the Requirements |
| Clarity of Solution | No.1 max |
| Colour of Solution | No.1 yellow or yellow-green max |
| Bacterial Endotoxins | 0.50 EU/mg max |
| Acidity pH | 3.0–5.5 |
| Water | 3.0%–6.0% |
| Residue on Ignition | 0.5% max |
| Aerobic bacteria | 1000 cfu/g max |
| Mold and yeast | 100 cfu/g max |
| Escherichia coli | Not detected |
| Acetone (Residual Solvent) | 500 ppm max |
| Butanol (Residual Solvent) | 1000 ppm max |
| Each single impurity peak area | Not greater than 1.0% of the reference solution peak area |
| Total impurity peak area | Not greater than 2.0% of the reference solution peak area |
| Lincomycin B | 5.0% max |
| Assay (HPLC) On the Dried Basis | Lincomycin (C₁₈H₃₄N₂O₆S) 82.5% min |
Applications
Lincomycin hydrochloride (CAS 859-18-7) is a clinically important antibiotic primarily used in veterinary and human medicine to treat bacterial infections caused by susceptible Gram-positive organisms. It is commonly applied in formulations for systemic and topical administration, including injectables, oral suspensions, and medicated feed for livestock and poultry. Lincomycin hydrochloride is effective against infections such as respiratory tract diseases, skin infections, and soft tissue infections, and it is frequently used to control staphylococcal and streptococcal infections. In pharmaceutical research and development, it serves as a reference standard or starting material for studying lincosamide antibiotics, antibiotic resistance mechanisms, and the synthesis of derivative compounds with improved pharmacokinetic or antibacterial profiles.
Benefits
The benefits of Lincomycin hydrochloride lie in its broad-spectrum activity against Gram-positive bacteria, potency at low concentrations, and well-established safety profile. Its hydrochloride salt form enhances water solubility, stability, and bioavailability, making it suitable for various dosage forms and routes of administration. Lincomycin hydrochloride provides targeted antibacterial action while minimizing disruption to beneficial gut flora when used appropriately in veterinary applications. Its clinical effectiveness, combined with well-documented pharmacological data, allows healthcare providers and veterinarians to employ it reliably for infection control. Additionally, its role as a research compound facilitates the development of new antibacterial agents and studies on resistance mitigation.
Conclusion
Lincomycin hydrochloride is a vital lincosamide antibiotic with wide applications in human and veterinary medicine. Its potent activity against Gram-positive bacteria, enhanced solubility, and stability make it a reliable choice for treating various infections. By offering efficacy, versatility in formulations, and a well-established safety profile, Lincomycin hydrochloride continues to be an essential agent in clinical therapy and pharmaceutical research.
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