CAS · 109-64-8
Product Overview
1,3-Dibromopropane is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Item | Specification |
|---|---|
| Appearance | Colorless or slightly yellow liquid |
| Assay | 99% min |
| pH | 6–8 |
| Water | 0.5% max |
Applications
1. Organic Synthesis
a. Alkylation Agent
● Used to introduce a three-carbon spacer between two nucleophilic moieties such as amines, thiols, phenols, or carboxylic acids.
● Facilitates the formation of:
Ethers
Thioethers
Amines
Cyclic compounds
b. Synthesis of Heterocycles
● 1,3-Dibromopropane is frequently used in the construction of five- or six-membered rings, especially:
Pyrrolidines
Piperidines
Oxazoles and thiazoles
● Acts as a templating reagent for ring-closing reactions.
2. Pharmaceutical and Agrochemical Intermediates
● Functions as a linker or building block in the synthesis of active pharmaceutical ingredients (APIs) and bioactive compounds.
● Used in the preparation of:
Antiviral and antimicrobial agents
Enzyme inhibitors
CNS-active agents
● Also found in intermediate steps for pesticides and fungicides where carbon chain length and reactivity are critical.
3. Polymer and Materials Chemistry
a. Crosslinking Agent
● Useful in the modification or crosslinking of polymers and resins, especially where a flexible C₃ spacer is desired.
● Applied in:
Polyurethane elastomers
Epoxy resin systems
Conductive and specialty polymers
b. Functional Monomer Synthesis
● Precursor to functionalized monomers used in making:
Ionic liquids
Zwitterionic compounds
Supramolecular materials
4. Industrial Applications
● Acts as an intermediate in the production of specialty chemicals.
● Employed in rubber additives, coating formulations, and plastic modifiers.
● Useful in the manufacture of quaternary ammonium salts and ionic surfactants.
Benefits
√ Versatile Bifunctional Reagent
● 1,3-Dibromopropane丨CAS 109-64-8 contains two bromine atoms that enable double substitution reactions.
● Ideal for constructing symmetric or bridged molecules.
√ Controlled Chain Length
● Provides a precise three-carbon spacer, critical in structure-activity relationships (SAR) in pharmaceuticals and materials.
√ High Reactivity
● Undergoes efficient nucleophilic substitution, making it suitable for diverse chemistries.
√ Readily Available and Cost-Effective
● Commercially available in bulk.
● Can be easily scaled for lab-scale or industrial production.
Conclusion
1,3-Dibromopropane丨CAS 109-64-8 is a highly reactive, bifunctional alkylating agent that plays a key role in organic synthesis, pharmaceutical development, and materials science. Its ability to introduce a C₃ linker and form varied chemical bonds makes it an essential intermediate in designing complex molecules, crosslinked polymers, and specialty chemicals.
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Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.