CAS · 7517-19-3
Product Overview
Leucine methyl ester hydrochloride is a high-purity amino-acid supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Property | Specification |
|---|---|
| Appearance | White crystalline powder |
| Assay | 98% min |
| Specific Rotation [22/D] (C=2 in H2O) | +12° ~ +14° |
| Water (K.F.) | 0.5% max |
Applications
1. Peptide Synthesis and Drug Development
√ Intermediate in Peptide Synthesis
● Leucine methyl ester hydrochloride丨CAS 7517-19-3 is commonly used in the synthesis of peptides and peptoid molecules, particularly in solid-phase peptide synthesis (SPPS).
● It helps protect the amino group during the peptide elongation process, preventing unwanted reactions and improving synthesis efficiency.
√ Prodrug Development
● The ester group in Leucine Methyl Ester Hydrochloride may be cleaved in vivo, thus acting as a prodrug form of leucine, providing controlled release of leucine after the ester is hydrolyzed in the body.
√ Biochemical Research
● Used in metabolic studies to investigate the metabolism of leucine and its impact on protein synthesis, muscle growth, and amino acid transport.
● Leucine derivatives are key in research focused on muscle protein metabolism and anabolic signaling pathways.
2. Nutraceutical and Sports Nutrition
√ Amino Acid Supplementation
● Leucine Methyl Ester Hydrochloride can be used in the formulation of amino acid supplements, especially in sports nutrition. As leucine is a major player in muscle recovery, its esterified form may be used for slow-release amino acid supplementation in protein powders or post-workout recovery formulations.
√ Muscle Protein Synthesis Stimulation
● Leucine is known to activate the mTOR pathway, which plays a critical role in muscle growth. As a supplement, this compound can enhance muscle protein synthesis in athletes and individuals involved in resistance training.
3. Cosmetic and Dermatological Applications
√ Skin Care and Anti-Aging Formulations
● Leucine, along with other amino acids, plays a role in the repair and regeneration of skin cells. It may be incorporated into cosmetic formulations, particularly for promoting skin elasticity, collagen synthesis, and anti-aging effects.
● Leucine derivatives like Leucine Methyl Ester Hydrochloride could be used in skin moisturizers and anti-wrinkle products to promote a youthful appearance.
4. Industrial and Biotechnological Applications
√ Biocatalysis and Enzyme Engineering
● As a chiral building block, leucine derivatives are used in the development of biocatalysts and enzyme-engineered reactions that require specific stereochemistry for synthesis, particularly in the formation of chiral amines or lactams.
√ Research in Branched-Chain Amino Acids (BCAAs)
● As a precursor to leucine and other BCAAs, Leucine Methyl Ester Hydrochloride is useful in research involving BCAA metabolism, muscle wasting diseases, and nutrition science.
Benefits
√ Enhanced Stability
● The methyl ester form of leucine makes the compound more stable and easier to handle compared to free leucine, which can be sensitive to heat and moisture.
√ Controlled Release
● As an ester, it can provide a controlled release of leucine in the body or in a system, which is beneficial in both drug delivery and nutritional supplements.
√ Versatility in Synthesis
● Leucine Methyl Ester Hydrochloride is a valuable intermediate in peptide and protein chemistry, especially in solid-phase peptide synthesis, where it facilitates the efficient coupling of leucine to other amino acids.
√ Improved Bioavailability
● Esterification of leucine can improve its lipophilicity, which may help enhance bioavailability and absorption in certain formulations, such as oral supplements or topical products.
√ Essential Amino Acid
● As leucine is an essential amino acid, it is crucial for muscle growth, tissue repair, and immune function. This derivative allows for its use in applications that require high-purity or controlled-release delivery of leucine.
Conclusion
Leucine methyl ester hydrochloride丨CAS 7517-19-3 is a versatile amino acid derivative with significant applications in peptide synthesis, drug delivery, sports nutrition, and cosmetic formulations. Its ability to enhance bioavailability, controlled release, and stability makes it a valuable compound for various industrial and research uses, particularly in biotechnology and biochemical studies.
Previous
4-Nitro-L-phenylalanine Monohydrate丨CAS 207591-86-4
Next
4-(4-Hydroxymethyl-3-methoxyphenoxy)butyric Acid丨CAS 136849-75-7
Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.