CAS · 71-00-1
Product Overview
L-Histidine is a high-purity nutrient-additives supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Grade: | USP 43 |
|---|---|
| Appearance: | White crystals or crystalline powder |
| Assay: | 98.5 to 101.5% |
| Residue on ignition: | 0.40% max |
| Chloride (Cl): | 0.05% max |
| Sulfate (SO₄): | 0.03% max |
| Iron (Fe): | 0.003% max |
| Individual impurity: | 0.5% max |
| Total impurities: | 2.0% max |
| Specific rotation [α]D25: | +12.6 to +14.0° |
| pH: | 7.0 to 8.5 |
| Loss on drying: | 0.20% max |
Applications
1. Nutritional Supplements & Medical Use
L-Histidine丨CAS 71-00-1 is an essential amino acid, particularly important during infancy, growth, and recovery from illness.
● Dietary supplements: Included in amino acid blends for muscle repair and growth.
● Parenteral and enteral nutrition: Used in IV amino acid formulations for patients with nutritional deficiencies.
● Infant formula: Added due to its critical role in growth and development.
2. Pharmaceutical Applications
L-Histidine is used as:
● A buffering agent: Due to its imidazole ring, it can stabilize pH in injectable formulations and biopharmaceutical products.
● A chelating agent: Forms complexes with metal ions, aiding in drug formulations and metal detox therapies.
● A component in biologics production: Helps stabilize proteins and monoclonal antibodies during formulation and storage.
3. Cell Culture & Biotech Research
● L-Histidine is a crucial component of cell culture media, particularly for yeast and mammalian cells.
● It plays a role in maintaining intracellular pH and as a precursor for histamine biosynthesis in biological systems.
4. Cosmetics & Personal Care
Due to its moisturizing and antioxidant properties, L-histidine is used in:
● Skin-care formulations to support hydration and natural repair processes.
● Hair products, especially for damaged or color-treated hair, as it can bind metals and help reduce oxidative damage.
5. Food Additive and Fortification
● Used in sports nutrition products, protein supplements, and fortified foods to support muscle recovery and immune function.
● As an essential amino acid, it helps meet dietary requirements in functional foods and health drinks.
Benefits
√ Histamine Production
L-Histidine丨CAS 71-00-1 acts as a precursor for histamine, a vital compound involved in immune responses, gastric acid secretion, and neurotransmission.
√ Metal Binding and Detoxification
L-Histidine can chelate heavy metals (e.g., copper, zinc, nickel), potentially protecting cells from metal-induced toxicity.
√ Antioxidant Properties
Scavenges reactive oxygen species (ROS), aiding in cellular defense mechanisms against oxidative stress.
√ Tissue Growth and Repair
Supports collagen synthesis, wound healing, and muscle maintenance, especially under stress or trauma.
√ pH Buffering in Protein Stability
Used in protein formulations for maintaining structural stability in vaccines and biologics.
Conclusion
L-Histidine丨CAS 71-00-1 is a vital amino acid with diverse applications across nutrition, pharmaceuticals, biotech, and personal care industries. Its unique biochemical properties-such as pH buffering, metal chelation, and antioxidation-make it indispensable in both therapeutic and commercial settings. Whether supporting infant growth, stabilizing biopharmaceuticals, or enhancing skin health, L-Histidine continues to play a crucial role in science and industry.
Previous
Next
Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.