CAS · 42461-84-7
Product Overview
Flunixin meglumin is a high-purity veterinary-medicine supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Property | Specification |
|---|---|
| Grade | USP40 |
| Appearance | A white to almost white, crystalline powder |
| Solubility | Freely soluble in water and methanol, practically insoluble in acetone |
| Identification 1 | Infrared absorption: 197M; Ultraviolet absorption: 197U |
| Identification 2 | Water: Free soluble; Ethanol (96%): Free soluble; Ethyl acetate: Practically insoluble |
| Appearance of solution | Clear and not more intensely coloured than reference solution Y7 |
| Purity (HPLC) | 98–102% |
| Melting Point | 137~140°C |
| pH (5% w/v water solution) | 7.0–9.0 |
| Related Substances | 2-chloropyridine-3-carboxylic acid: 0.2% max 2-methyl-3-(trifluoromethyl)aniline: 0.2% max Ethyl 2-chloropyridine-3-carboxylate: 0.2% max Ethyl 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylate: 0.2% max |
| Impurities | Single impurity: 0.2% max Unknown impurity: 0.2% max Total impurities (1–2): 0.5% max |
| Specific optical rotation | -9.0° to -12.0° |
| Isopropanol | 0.5% max |
| Ethanol | 0.5% max |
| Bacterial endotoxins | 1 EU/mg max |
| Loss on drying | 0.5% max |
| Sulphated ash | 0.1% max |
| Residue on ignition | 0.2% max |
| Colour of solution | Clear, less coloured than reference solution Y6 |
| Clarification | 1.2 g flunixin meglumine / 8.8 g water |
| Explanation | Micronisation 200±20 μm |
Applications
1. Veterinary Anti-inflammatory Agent
Flunixin meglumin丨CAS 42461-84-7 is widely administered to livestock and companion animals to manage pain and inflammation resulting from:
● Musculoskeletal disorders (e.g., lameness, arthritis)
● Colic in horses
● Respiratory tract infections
● Mastitis and metritis in cattle
● Post-surgical pain management
It is particularly favored for its rapid onset of action and long-lasting effect (up to 24–36 hours in some species).
2. Antipyretic (Fever-Reducing) Agent
In livestock, flunixin meglumine is effective in reducing fever associated with infections or systemic diseases, especially during outbreaks of viral or bacterial illnesses.
● Often used in conjunction with antimicrobial therapy to improve clinical outcomes.
● Commonly used during shipping fever complex in cattle and equine viral respiratory infections.
3. Endotoxemia and Septic Shock Management
Flunixin meglumine plays a critical role in treating endotoxemia in horses and cattle by:
● Inhibiting the effects of endotoxins released by Gram-negative bacteria
● Reducing inflammation-mediated organ damage
● Supporting circulatory and gastrointestinal function in critical care
Benefits
1. Potent and Fast-Acting
Flunixin meglumine provides rapid relief, with measurable anti-inflammatory and analgesic effects occurring within 2 hours of administration. This is particularly important in acute pain scenarios like colic or trauma.
2. Extended Duration of Action
Its long half-life in animals means that once-daily dosing is often sufficient, improving treatment compliance and minimizing handling stress in animals.
3. Broad Spectrum of Use
Approved for use in multiple species including horses, cattle, swine, and companion animals. Its efficacy across various inflammatory conditions makes it a versatile tool in veterinary practice.
4. Synergistic Use with Other Therapies
Often used alongside antibiotics, rehydration, or supportive therapies to improve the recovery of animals with systemic or infectious illnesses.
5. Regulatory Approval and Safety
Flunixin meglumin丨CAS 42461-84-7 is approved by regulatory bodies like the FDA and EMA for veterinary use, with clearly established withdrawal times for milk and meat in food-producing animals, ensuring safe and responsible use.
Previous
Penicillin G Potassium丨CAS 113-98-4
Next
Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.