CAS · 2524-64-3
Product Overview
Diphenyl chlorophosphate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Colorless liquid |
|---|---|
| Purity(GC): | 99% min |
| PDCP: | 0.5% max |
| TPP: | 0.5% max |
| Single impurity: | 0.5% max |
Applications
1. Phosphorylation Agent
Used to introduce diphenyl phosphate groups into alcohols, phenols, or amines.
Converts hydroxyl-containing compounds into their phosphoric acid esters-important in synthesizing biologically active molecules.
2. Reagent in Organic Synthesis
Functions as an activating agent in the synthesis of peptides, nucleotides, and other biomolecules.
Used in selective protection and deprotection strategies in multi-step syntheses.
3. Intermediate for Flame Retardants
Serves as a precursor in the manufacture of phosphate-based flame retardants, particularly for plastics and synthetic fibers.
4. Modifier in Polymer Chemistry
Used in the functionalization of polymers, resins, and other materials to impart flame-retardant or plasticizing properties.
5. Cross-Coupling and Linker Chemistry
Applied in the preparation of linkers or spacers in bioconjugation and medicinal chemistry, especially when a phosphoryl group is needed.
Benefits
✅ Highly Reactive Phosphoryl Donor
DPCP is very effective in introducing phosphoryl groups under mild conditions, making it suitable for delicate or sensitive substrates.
✅ Broad Functional Group Compatibility
Compatible with alcohols, amines, and phenols, enabling its use in complex organic syntheses.
✅ Industrial Versatility
Valuable in pharmaceutical, polymer, and materials science fields for its ability to modify molecules and materials.
✅ Efficient Synthesis of Organophosphates
Useful in synthesizing diphenyl phosphate esters, which can act as intermediates, flame retardants, or biologically active compounds.
Conclusion
Diphenyl chlorophosphate (DPCP) is a valuable phosphorylating reagent widely employed in organic synthesis, flame retardant production, and polymer modification. Its ability to form diphenyl phosphate esters efficiently and its compatibility with diverse functional groups make it an essential tool in chemical synthesis. Proper handling and moisture control are essential to ensure safe and effective use.
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