CAS · 1060802-23-4
Product Overview
5-Bromo-2-chloropyridine-4-carbaldehyde is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Light yellow powder |
|---|---|
| Purity (GC) | 97% min |
| Identification | HNMR confirms |
| Total Impurity | 3% max |
| Single Impurity | 2% max |
| Water Content | 0.5% max |
Applications
5-Bromo-2-chloropyridine-4-carbaldehyde (CAS 1060802-23-4) is a halogenated pyridine derivative widely used as an intermediate in organic synthesis and pharmaceutical research. Its functional groups - bromine, chlorine, and an aldehyde - make it a versatile building block for the preparation of heterocyclic compounds, active pharmaceutical ingredients (APIs), and agrochemicals. In medicinal chemistry, it is employed to develop drug candidates with enhanced bioactivity by allowing structural modifications that improve receptor binding and pharmacokinetics. Additionally, it serves in the synthesis of specialty fine chemicals and advanced materials where halogenated pyridine frameworks are required.
Benefits
The main benefits of 5-bromo-2-chloropyridine-4-carbaldehyde come from its multifunctional reactivity and structural diversity. The bromine and chlorine substituents enable selective cross-coupling reactions such as Suzuki, Heck, and Sonogashira couplings, while the aldehyde group allows further derivatization through condensation or reduction reactions. This combination gives chemists flexibility in designing complex molecules with tailored biological or material properties. Its stability under controlled conditions and compatibility with modern synthetic techniques make it a reliable reagent for advanced chemical development. Moreover, its use in drug discovery accelerates the creation of novel therapeutic candidates, particularly in the fields of oncology, neurology, and infectious diseases.
Conclusion
In summary, 5-bromo-2-chloropyridine-4-carbaldehyde is a valuable synthetic intermediate with broad applications in pharmaceuticals, agrochemicals, and fine chemical research. Its multifunctional groups provide diverse reaction pathways, making it a powerful tool for building complex and bioactive molecules. With its combination of stability, reactivity, and versatility, this compound continues to support progress in chemical innovation and drug development.
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