CAS · 7579-36-4
Product Overview
Dibenzyl oxalate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White or off-white solid |
|---|---|
| LCMS: | Spectrum is consistent with exact mass and structure |
| H-NMR: | Spectrum is consistent with structure |
| IR: | Spectrum is consistent with structure |
| Purity (HPLC): | ≥98.0% |
| Purity (GC): | ≥98.0% |
| Individual Impurities (GC): | ≤1.0% |
| Report all Impurities by RRT: | - |
| Water Content (KF): | ≤0.5% |
| Residue on Ignition (ROI): | ≤0.5% |
| Loss on Drying (LOD): | ≤0.5% |
| Residual Solvents (GC): | ≤0.5% |
| QNMR (w/w): | ≥98.0% |
Applications
Dibenzyl oxalate is an important organic ester used primarily as an intermediate in organic synthesis and pharmaceutical chemistry. It serves as a versatile reagent for the preparation of oxalate derivatives, heterocycles, and fine chemicals. Its reactive ester groups enable transformations such as hydrolysis, transesterification, and nucleophilic substitution, facilitating the synthesis of diesters, amides, and cyclic compounds. In medicinal chemistry, dibenzyl oxalate is employed in the construction of active pharmaceutical intermediates and as a building block for the development of antitumor, antiviral, and enzyme-inhibiting molecules. Additionally, it finds use in chemical research for esterification reactions, mechanistic studies, and the preparation of novel organic compounds with tailored functionality.
Benefits
The benefits of dibenzyl oxalate derive from its high reactivity, solubility in organic solvents, and stability under standard laboratory conditions. The benzyl ester groups provide protective functionalities that can be selectively removed under mild conditions, allowing precise multi-step syntheses. Its symmetrical diester structure enables efficient incorporation into a variety of synthetic pathways, yielding high-purity products. Additionally, dibenzyl oxalate offers predictable chemical behavior, which ensures reproducibility in research and industrial applications. Its versatility as both a functional intermediate and a protected oxalate source makes it a valuable tool for designing complex molecules in pharmaceuticals and fine chemical production.
Conclusion
Dibenzyl oxalate is a versatile organic intermediate with wide-ranging applications in pharmaceutical synthesis, organic chemistry, and fine chemical research. Its reactive ester groups, stability, and solubility make it an ideal building block for producing oxalate derivatives, heterocycles, and bioactive compounds. By enabling efficient and controlled chemical transformations, dibenzyl oxalate continues to support innovation in drug development and advanced organic synthesis.
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