CAS · 2392-39-4
Product Overview
Dexamethasone 21-phosphate disodium salt is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White or slightly yellow, crystalline powder |
|---|---|
| Solubility | Freely soluble in water; slightly soluble in alcohol; very slightly soluble in dioxane; insoluble in chloroform and in ether |
| Optic Rotation | +74°～+82° |
| Inorganic phosphates | 1.0% max |
| Water | 10.0% max |
| pH | 7.5～10.5 |
| Limit of Phosphate ions | 1.0% max |
| Limit of Alcohol | 1.5% max |
| Ethanol | 8.0% max |
| Related Substances | |
| Dexamethasone | ≤0.5% |
| Individual impurities | ≤0.5% |
| Total impurities | ≤1.0% |
| Assay | 97.0%～102.0% |
Applications
Pharmaceutical Industry
Dexamethasone 21-phosphate disodium salt丨2392-39-4 is widely used as an anti-inflammatory and immunosuppressive drug. It is a water-soluble corticosteroid derivative of dexamethasone, making it suitable for intravenous and ophthalmic administration. It is used to treat conditions such as severe allergic reactions, autoimmune diseases, asthma, and rheumatoid arthritis.
Oncology and Chemotherapy
This compound is often used as part of cancer treatment regimens to reduce inflammation and manage side effects caused by chemotherapy, such as nausea and swelling. It also helps in reducing cerebral edema in brain tumor patients.
Ophthalmic Treatments
Dexamethasone 21-phosphate disodium salt is formulated into eye drops for treating eye inflammation, post-surgical swelling, and allergic conjunctivitis due to its potent anti-inflammatory properties.
Respiratory and COVID-19 Treatment
During the COVID-19 pandemic, dexamethasone and its derivatives, including this salt form, have been used to manage severe inflammation in hospitalized patients requiring oxygen or ventilation support.
Veterinary Medicine
It is used in veterinary applications for treating inflammatory and immune-related conditions in animals, including arthritis, allergies, and respiratory issues.
Benefits
Rapid Absorption and High Solubility
The disodium phosphate salt form enhances the solubility and absorption of dexamethasone, making it more effective for intravenous and ophthalmic applications.
Powerful Anti-Inflammatory and Immunosuppressive Effects
As a corticosteroid, it effectively reduces inflammation, swelling, and immune overreactions, making it essential for treating various chronic and acute conditions.
Supports Chemotherapy and Cancer Management
Its role in cancer treatment helps improve patient comfort by managing chemotherapy-induced side effects and reducing tumor-related swelling.
Effective in Severe Respiratory Conditions
Its ability to manage inflammation in lung diseases, including severe COVID-19 cases, highlights its importance in respiratory medicine.
Versatile Use Across Medical Fields
From neurology to ophthalmology, respiratory medicine, and veterinary applications, dexamethasone 21-phosphate disodium salt is a crucial pharmaceutical agent with broad medical relevance.
Conclusion
Dexamethasone 21-phosphate disodium salt丨2392-39-4 is a highly effective and widely used corticosteroid with applications in human and veterinary medicine. Its rapid solubility, strong anti-inflammatory effects, and role in cancer treatment and respiratory diseases make it a valuable compound for managing various serious health conditions.
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