CAS · 31166-44-6
Product Overview
Benzyl 1-piperazinecarboxylate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | Light yellow to yellow liquid |
|---|---|
| Purity (GC) | 98% min |
| HNMR | Confirms to structure |
| Water (KF) | 1.0% max |
Applications
Benzyl 1-piperazinecarboxylate is an important organic intermediate widely used in pharmaceutical and fine chemical synthesis. It is commonly employed as a protected piperazine building block in the preparation of active pharmaceutical ingredients, drug candidates, and bioactive molecules, particularly in the fields of central nervous system, cardiovascular, and anti-infective therapeutics. The compound is also used in medicinal chemistry research for the construction of piperazine-containing libraries during lead optimization and structure–activity relationship studies. Additionally, benzyl 1-piperazinecarboxylate finds application in the synthesis of agrochemical intermediates and specialty chemicals where controlled functionalization of the piperazine moiety is required.
Benefits
Benzyl 1-piperazinecarboxylate offers several advantages due to its chemical stability and protective functionality. The benzyl carbamate group effectively protects the piperazine nitrogen during multi-step synthesis, allowing for selective reactions and improved process control. It is compatible with a wide range of reaction conditions and can be conveniently removed under mild hydrogenation or deprotection conditions. The compound exhibits good purity and reproducibility, supporting reliable synthesis in both laboratory and industrial environments. Its versatility as a synthetic intermediate enables efficient access to structurally diverse piperazine derivatives.
Conclusion
Benzyl 1-piperazinecarboxylate is a valuable protected piperazine intermediate with broad applications in pharmaceutical development, medicinal chemistry, and fine chemical synthesis. Its benefits, including stability, selective protection, ease of deprotection, and synthetic flexibility, make it an essential building block for the efficient construction of complex bioactive molecules. Continued use of this compound supports innovation in drug discovery and specialty chemical manufacturing.
Previous
Tert-Butyl (mesitylsulfonyl)oxycarbamate丨CAS 36016-39-4
Next