CAS · 1405-87-4
Product Overview
Bacitracin is a high-purity a-api supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Property | Specification |
|---|---|
| Grade | EP10.5 |
| Appearance | White or almost white, hygroscopic powder |
| Microbial assay (dried basis) | 60 IU/mg |
| Identification | HPLC, Conforms; Meets composition test; No white precipitate |
| pH | 6–7 |
| Loss on drying | 5% max |
| Sulfated Ash | 1% max |
| Content of Bacitracin A | 45% min |
| Sum of Bacitracin A, B1, B2, B3 | 77% min |
| Sum of impurities L, N | 8% max |
| Impurity E | 4% max |
| Impurity A | 3.5% max |
| Impurity B | 3% max |
| Impurity M | 3% max |
| Impurity C | 2.5% max |
| Sum of impurities O, P, Q | 2.5% max |
| Sum of impurities F, G | 2% max |
| Impurity H | 1% max |
| Any other impurity | 2% max |
| Total impurities | 23% max |
| Total viable aerobic count | 100 cfu/g max |
| Particle size | Min. 99% ≤ 20 µm by volume |
Applications
1. Topical Antibiotic for Skin Infections
Bacitracin is widely used in over-the-counter ointments and creams to treat:
● Minor cuts, scrapes, and burns: Prevents infection by inhibiting bacterial cell wall synthesis.
● Dermatitis and localized bacterial skin infections: Effective against Staphylococcus and Streptococcus species.
Often combined with other antibiotics (e.g., neomycin or polymyxin B) for broader-spectrum coverage.
2. Ophthalmic Preparations
Used in eye ointments for treating bacterial conjunctivitis and blepharitis, due to its efficacy and gentle action on sensitive tissues.
● Sterile formulations: Designed for safe application to ocular surfaces.
3. Veterinary Medicine
Bacitracin丨CAS 1405-87-4 is also used in veterinary formulations for treating skin infections in animals and previously as a growth promoter in livestock (though restricted in many countries due to resistance concerns).
● Topical sprays and powders: Help control infection in wounds and surgical sites for pets and livestock.
4. Pharmaceutical Manufacturing
Employed as a preservative or bioburden control agent in certain pharmaceutical processes and cell culture media, particularly where Gram-positive contamination is a risk.
Benefits
1. Effective Against Gram-Positive Bacteria
Bacitracin丨CAS 1405-87-4 inhibits bacterial cell wall synthesis, making it potent against Gram-positive pathogens like Staphylococcus aureus, including some MRSA strains in topical applications.
2. Low Systemic Toxicity
When used topically, bacitracin exhibits minimal systemic absorption, reducing the risk of systemic side effects and making it safe for short-term skin application.
3. Synergy with Other Antibiotics
Often formulated in triple antibiotic ointments for synergistic and broader antimicrobial activity, reducing the chance of resistance development.
4. Ease of Use and Accessibility
Available in non-prescription (OTC) forms, bacitracin is a convenient first-line treatment for preventing infection in minor wounds and injuries.
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Conclusion
A concise summary and suitability assessment for this product is available on request. Contact our team to discuss whether it fits your process and quality requirements.