alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol
CAS 24155-42-8
CAS · 24155-42-8
Product Overview
alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol丨24155-42-8 is a heterocyclic compound that contains both an imidazole ring and a chlorophenyl group. It is part of the imidazole family, which is well-known for its bioactive properties. This compound has demonstrated usefulness in pharmaceutical research, particularly as an antifungal or antimicrobial agent.
Product Specifications
| Property | Specification |
|---|---|
| Appearance | White to almost white powder |
| IR spectrum | Conforms to the standard |
| Melting range | 133-138°C |
| Optical rotation angle (10% methanol) | 0±0.4° |
| Sulfated ash | 0.1% max |
| Related substances (HPLC) | alpha-(2, 4-dichlorophenyl)-2-chloro-ethanol: 0.05% max. 1-(2,5-Dichlorophenyl)-2-(1H-imidazole-1-yl)ethanol: 0.1% max. 1-(3,4-Dichlorophenyl)-2-(1H-imidazole-1-yl)ethanol: 0.1% max. 1-(2,4-Dichlorophenyl)-2-(2-methylimidazol-1-yl)ethanol: 0.05% max. 1-(2,4-Dichlorophenyl)-2-(4-methylimidazol-1-yl)ethanol: 0.05% max. 1-(2,4-Dichlorophenyl)-2-(5-methylimidazol-1-yl)ethanol: 0.05% max. |
| Each other impurity | 0.5% max |
| Sum of impurities | 1.0% max |
| Loss on drying | 0.5% max |
| Chromatographic purity (HPLC) | 99% min |
| Potentiometric assay | 98-101.0% |
Applications
1. Pharmaceutical Industry
● Antifungal and Antimicrobial Research:
Investigated for its antifungal properties, potentially useful in the treatment of fungal infections, particularly in dermatological applications.
● Drug Development:
Serves as a building block in the synthesis of other bioactive molecules, especially in the development of antimicrobial agents targeting fungal and bacterial infections.
● Enzyme Inhibition:
Shows potential for inhibiting enzymes involved in microbial metabolism, a mechanism critical to many pharmaceutical formulations.
2. Agrochemical Applications
● Pesticide and Herbicide Research:
Used in the development of pesticides and herbicides, particularly those targeting fungal pathogens that affect crops.
3. Laboratory Use
● Chemical Reagent:
Used in synthetic chemistry for creating imidazole derivatives and other heterocyclic compounds with targeted biological activity.
Benefits
1. Strong Antimicrobial and Antifungal Properties
● Exhibits significant activity against fungal pathogens, making it useful in antifungal formulations for both medical and agricultural purposes.
2. Bioactive Heterocyclic Compound
● Its imidazole ring structure, common in many bioactive molecules, makes it a useful component in developing new drugs and antimicrobial agents.
3. Versatile Synthetic Intermediary
● Useful as a precursor for the development of more complex chemical agents, particularly in pharmaceuticals and agrochemicals.
Conclusion
alpha-(2,4-Dichlorophenyl)-1H-imidazole-1-ethanol丨24155-42-8 is a bioactive imidazole derivative with antifungal and antimicrobial properties. It plays a significant role in pharmaceutical research for the development of antimicrobial agents and serves as a versatile intermediate in chemical synthesis. Its applications extend to agrochemicals and laboratory research, making it valuable in the production of bioactive compounds.
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