CAS · 183133-94-0
Product Overview
7,10-Dimethoxy-10-DAB III is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White or almost white crystalline powder |
|---|---|
| Purity (HPLC) | 98% min |
| Identification (HPLC) | The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay |
| Loss on drying | 1.0% max |
| Total impurity | 2.0% max |
| Unknown single impurity | 1.0% max |
Applications
7,10-Dimethoxy-10-DAB III is a highly specialized natural product derivative used primarily in pharmaceutical research, medicinal chemistry, and natural product synthesis. It serves as a key intermediate and reference compound in the synthesis of complex alkaloids, antineoplastic agents, and bioactive molecules. In drug discovery, it is applied to explore cytotoxic, anticancer, and enzyme-inhibiting activities, particularly in the development of chemotherapeutic agents derived from plant alkaloids. Its defined stereochemistry and functional groups make it suitable for use in structure–activity relationship (SAR) studies, providing insights into pharmacophore optimization. Additionally, 7,10-Dimethoxy-10-DAB III is employed in synthetic methodology research, enabling the study of selective methylation, hydroxylation, and alkaloid functionalization reactions.
Benefits
The benefits of 7,10-Dimethoxy-10-DAB III arise from its well-defined molecular structure, stereochemical integrity, and synthetic versatility. Its dimethoxy functionalization enhances solubility, chemical stability, and compatibility with diverse reaction conditions, enabling selective transformations and incorporation into complex molecular frameworks. The compound's stereochemistry supports reproducible synthesis of chiral intermediates and analogs, which is critical in medicinal chemistry research. It is compatible with common organic solvents and reagents, facilitating laboratory-scale reactions, analytical studies, and bioactivity assays. Its high purity and well-characterized properties ensure reliability in drug development, SAR studies, and natural product synthesis.
Conclusion
7,10-Dimethoxy-10-DAB III is a valuable intermediate and research compound in the fields of pharmaceutical chemistry, natural product synthesis, and bioactive molecule development. Its functionalized, stereochemically defined structure supports selective chemical transformations, SAR studies, and the development of potential therapeutic agents. By enabling efficient synthesis, structural optimization, and pharmacological research, 7,10-Dimethoxy-10-DAB III continues to play an important role in advanced medicinal chemistry and natural product research.
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