CAS · 933-67-5
Product Overview
7-Methylindole is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | Off white light yellow powder |
|---|---|
| Purity (HPLC): | 98.0% min. |
| Melting Point: | 80–84°C |
| Loss on drying: | 0.5% max. |
| Residue on ignition: | 0.5% max. |
| 1H-NMR: | Conforms to structure |
| IR: | Conforms to reference |
Applications
1. Pharmaceutical Intermediate
Drug Synthesis: 7-Methylindole serves as a valuable building block in the synthesis of a variety of pharmacologically active compounds, including:
Antidepressants
Anticancer agents
Antimicrobial agents
Heterocyclic Scaffold: As an indole derivative, it forms the backbone of many bioactive molecules, playing a crucial role in drug discovery and development.
2. Agrochemical Synthesis
Used in the production of pesticides, herbicides, and fungicides.
Its indole structure contributes to the synthesis of plant growth regulators and other agrochemically active compounds.
3. Organic Synthesis
Functions as a starting material for constructing more complex indole derivatives via electrophilic substitution, cross-coupling reactions, and oxidation.
Participates in C–H activation chemistry and palladium-catalyzed functionalizations for synthetic and academic research.
4. Dye and Pigment Industry
Occasionally used in the development of specialty dyes and pigments due to its aromatic and chromophoric characteristics.
Benefits
Synthetic Flexibility: The indole ring is reactive and versatile, allowing diverse chemical modifications at various positions.
Pharmacophore Potential: As part of the indole family, 7-methylindole mimics structures found in many natural products and neurotransmitters like serotonin.
High Purity Availability: Commercially available in high purity, making it suitable for both research and industrial applications.
Research Utility: Widely used in medicinal chemistry and chemical biology for structure–activity relationship (SAR) studies.
Conclusion
7-Methylindole (CAS 933-67-5) is a key indole derivative with broad applications in pharmaceutical, agricultural, and synthetic chemistry. Its functional indole framework and chemical reactivity make it a valuable intermediate in the synthesis of high-value products. As the demand for novel heterocyclic compounds grows in medicinal and agrochemical development, the utility of 7-methylindole continues to expand in both industrial and academic settings.
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