CAS · 5165-28-6
Product Overview
5,5-Dimethylpyrrolidin-2-one is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White to Brown Solid |
|---|---|
| Purity: | 98% min |
| 1H NMR Spectrum: | Conforms to Structure |
| Water (KF): | 1.0% max |
Applications
5,5-Dimethylpyrrolidin-2-one (CAS 5165-28-6) is a cyclic amide (lactam) widely used as a solvent, chemical intermediate, and reagent in organic synthesis. Its structure, featuring a pyrrolidone ring with two methyl groups at the 5-position, provides high chemical stability and polarity, making it suitable for dissolving a wide range of organic and inorganic compounds. It is employed in pharmaceutical research as a building block for the synthesis of bioactive heterocycles, including CNS-active agents and enzyme inhibitors. Additionally, it is used in polymer chemistry, coatings, and materials science to modify resin properties, enhance solubility of additives, and serve as a medium for chemical reactions.
Benefits
The benefits of 5,5-dimethylpyrrolidin-2-one derive from its chemical stability, high polarity, and versatility in synthesis. The methyl groups increase steric hindrance, improving the stability of the lactam ring against hydrolysis and oxidation. Its polarity and solubility properties make it an effective solvent for polar and nonpolar compounds, facilitating reactions and formulations. In pharmaceutical and materials applications, it serves as a reliable intermediate and reaction medium, enabling the efficient construction of heterocyclic compounds, polymers, and functionalized materials. Its low volatility and chemical inertness also contribute to safer handling in laboratory and industrial settings.
Conclusion
5,5-Dimethylpyrrolidin-2-one is a versatile lactam with broad applications as a solvent, intermediate, and reagent in pharmaceuticals, materials science, and chemical synthesis. Its stability, polarity, and reactivity make it valuable for constructing bioactive heterocycles, polymers, and specialty materials. By supporting efficient synthesis and enhancing chemical performance, it remains an important tool in research, development, and industrial applications.
Previous
Next
Methyl 5-bromo-2-chloropyridine-3-carboxylate丨CAS 78686-79-0