CAS · 41468-25-1
Product Overview
Pyridoxal 5-phosphate monohydrate is a high-purity pharmaceutical-intermediates supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Description | Slightly yellow or off-white crystalline powder |
|---|---|
| Identification | The retention time of the main peak of the sample solution is consistent with that of the standard solution |
| Solubility | Very slightly soluble in water, soluble in alkali-OH solution |
| Melting point | 140℃ ~ 145℃ |
| Water (by KF) | 10% max |
| pH (in 0.25% water) | 2.6 ~ 3.0 |
| Heavy metals | 10 ppm max |
| Lead (Pb) | 0.5 ppm max |
| Arsenic (As) | 1.5 ppm max |
| Cadmium (Cd) | 0.5 ppm max |
| Mercury (Hg) | 0.1 ppm max |
| Toluene | 890 ppm max |
| Ethanol | 5000 ppm max |
| Particle size | 100% through 30 mesh |
| Pyridoxine HCl | 0.05% max |
| Purity (by HPLC) | 99% min |
| Assay (on dried basis) | 98.5% ~ 101% |
| Total Plate Count | 1000 cfu/g max |
| Yeast & Mold | 100 cfu/g max |
| Salmonella spp. | Negative |
| Escherichia coli | Negative |
| Staphylococcus aureus | Negative |
| Pseudomonas aeruginosa | Negative |
Applications
Pyridoxal 5-phosphate monohydrate (PLP), the active coenzyme form of vitamin B6, plays a crucial role in numerous enzymatic reactions. It is widely used in the pharmaceutical and nutraceutical industries as a supplement for supporting amino acid metabolism, neurotransmitter synthesis, and hemoglobin production. In clinical applications, it is utilized in managing conditions such as vitamin B6 deficiency, seizures in infants, homocystinuria, and certain types of anemia. In research, it is a key tool for studying enzyme mechanisms and biochemical pathways involving amino acid metabolism.
Benefits
The benefits of Pyridoxal 5-phosphate monohydrate are rooted in its essential role as a cofactor in over 100 enzymatic reactions. It helps regulate neurotransmitter balance, thereby supporting mood, cognitive function, and nervous system health. Its involvement in homocysteine metabolism contributes to cardiovascular protection, while its role in hemoglobin synthesis supports oxygen transport and energy metabolism. As a supplement, PLP offers enhanced bioavailability compared to pyridoxine, making it particularly effective for individuals with metabolic impairments or conditions requiring direct active B6 support.
Conclusion
Pyridoxal 5-phosphate monohydrate is a vital bioactive form of vitamin B6 with significant applications in medicine, nutrition, and research. Its ability to function as a coenzyme in numerous biochemical processes makes it essential for nervous system health, cardiovascular protection, and metabolic efficiency. With its superior bioavailability, PLP stands as a valuable compound for both preventive healthcare and therapeutic support.
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