CAS · 23135-50-4
Product Overview
5-(Carbobenzoxyamino)valeric acid is a high-purity amino-acids supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance | White or off-white powder |
|---|---|
| Purity (by HPLC) | 98% min |
| Water | 1% max |
| Assay | 98% min |
Applications
5-(Carbobenzoxyamino)valeric acid (CAS 23135-50-4) is a protected amino acid derivative commonly used in peptide synthesis and medicinal chemistry. The carbobenzoxy (Cbz) protecting group safeguards the amino functionality, allowing selective incorporation into peptides while preventing undesired side reactions. It serves as a building block for the synthesis of bioactive peptides, peptidomimetics, and pharmaceutical intermediates, including enzyme inhibitors and receptor-targeting molecules. Additionally, it is applied in research to study peptide structure–activity relationships (SAR), enzyme interactions, and protein engineering. Its defined stereochemistry and functional protection enable precise assembly of complex peptide sequences and incorporation into modified or functionalized peptides.
Benefits
The benefits of 5-(Carbobenzoxyamino)valeric acid stem from its chemical stability, stereochemical integrity, and compatibility with standard peptide synthesis protocols. The Cbz group allows mild deprotection under hydrogenation or acidic conditions, minimizing damage to sensitive residues. Its high optical purity ensures accurate incorporation of the L-valeric acid backbone into peptides, preserving biological activity and conformational properties. The compound is soluble in common organic solvents used for peptide coupling, facilitating efficient reactions and reproducible yields. These features make it a reliable intermediate for the synthesis of complex, bioactive, and structurally defined peptides in both laboratory and industrial settings.
Conclusion
5-(Carbobenzoxyamino)valeric acid is a valuable protected amino acid for peptide synthesis and medicinal chemistry. Its Cbz-protected amino group, stereochemical purity, and chemical stability enable precise assembly of peptides and bioactive molecules. By supporting efficient, reproducible, and selective peptide synthesis, it remains an essential building block in pharmaceutical development and peptide-based research.
Previous
L-Cyclohexylalanine丨CAS 27527-05-5
Next