CAS · 19427-28-2
Product Overview
N-Formyl-L-aspartic acid is a high-purity amino-acids supplied for industrial and specialty chemical applications. Contact our team for specifications, packaging options and lead times.
Product Specifications
| Appearance: | White to off-white powder |
|---|---|
| Purity (HPLC): | 98% min |
| Clarity of solution: | 0.1 g in 2 mL DMF, clear solution |
| IR Spectrum: | In accordance with the structure |
| Mass Spectrum: | In accordance with the structure |
| NMR Spectrum: | In accordance with the structure |
Applications
N-Formyl-L-aspartic acid is a formylated amino acid derivative widely used in peptide synthesis, medicinal chemistry, and biochemical research. The formyl group protects the amino functionality, allowing selective reactions at the carboxyl groups or incorporation into peptide chains without unwanted side reactions. It serves as a key intermediate for synthesizing aspartic acid-containing peptides, enzyme inhibitors, and bioactive molecules. In research, N-Formyl-L-aspartic acid is employed to study enzyme specificity, peptide conformations, and protein interactions. It also finds application in the development of pharmaceuticals, particularly in producing analogs with improved metabolic stability, targeted delivery, and enhanced biological activity.
Benefits
The formyl protection provides significant synthetic advantages by preventing side reactions and ensuring controlled peptide coupling. N-Formyl-L-aspartic acid is chemically stable, easy to handle, and soluble in common organic solvents, making it suitable for both solution-phase and solid-phase synthesis. Its use allows for high yields and reproducibility in multi-step syntheses, retaining the stereochemistry of the L-aspartic acid moiety. The compound also enables selective deprotection under mild acidic or basic conditions, yielding free amino acids or peptides for further functionalization. These properties make it a versatile building block for creating complex peptides and bioactive derivatives efficiently and reliably.
Conclusion
N-Formyl-L-aspartic acid is a valuable protected amino acid for peptide synthesis, biochemical research, and pharmaceutical development. Its formyl group ensures selective reactivity, stability, and versatility, supporting the efficient construction of aspartic acid-containing peptides and bioactive molecules. By enabling precise and high-yield synthesis, this compound continues to be an important tool in medicinal chemistry and advanced peptide research.
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